N-decanoyl-L-Homoserinelactone , ≥96% , 177315-87-6

Synonym(s):
N-[(3S)-Tetrahydro-2-oxo-3-furanyl]decanamide;C10-HSL

CAS NO.：177315-87-6

Empirical Formula: C14H25NO3

Molecular Weight: 255.35

MDL number: MFCD11113140

PRODUCT Properties

• Melting point: 127-130 °C
• Boiling point: 466.1±34.0 °C(Predicted)
• Density: 1.02±0.1 g/cm3(Predicted)
• storage temp.: -20°C
• solubility: DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:4): 0.2 mg/ml; DMSO: 20 mg/ml
• form: A crystalline solid
• pka: 14.72±0.20(Predicted)
• color: White to off-white
• optical activity: [α]/D -24±3°, c = 0.2 in methanol

Description and Uses

Decanoyl-L-homoserine lactone is an active quorum sensing modulator first recognised in Burkholderia pseudomallei. Decanoyl-L-homoserine lactone and other acylhomoserine lactones have been detected in hundreds of bacterial species and, while the homologues vary between species and strains, the homoserine lactones are the major chemical modulators of within and between cell communication and regulation. The most significant variable defining the function of the homoserine lactone is the length of the acyl chain, with shorter chains displaying opposing actions to the longer chains.

Safety

• WGK Germany: 3