Home Categories Pharmaceutical intermediates Diethyl 5-Amino-3-methyl-2,4-thiophenedicarboxylate
A3591412

Diethyl 5-Amino-3-methyl-2,4-thiophenedicarboxylate , >98.0%(GC) , 4815-30-9

CAS NO.:4815-30-9

Empirical Formula: C11H15NO4S

Molecular Weight: 257.31

MDL number: MFCD00005450

EINECS: 225-388-0

Pack Size Price Stock Quantity
5G RMB140.00 In Stock
25G RMB450.40 In Stock
100G RMB1481.60 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 105-108 °C(lit.)
Boiling point: 372.6±37.0 °C(Predicted)
Density  1.3137 (rough estimate)
refractive index  1.5500 (estimate)
pka -0.53±0.10(Predicted)
form  Crystalline Powder
color  Slightly yellow to beige-yellow
CAS DataBase Reference 4815-30-9(CAS DataBase Reference)

Description and Uses

Diethyl 5-Amino-3-methylthiophene-2,4-dicarboxylate is used as a reagent in the synthesis of novel pyrazolo-pyrimidinones as dipeptidyl peptidase IV (DPP-IV) inhibitors in diabetes. It is also used in the synthesis of N-phenylthieno[2,3-d]pyrimidin-4-amines which act as inhibitors of fibroblast grow factor receptor 1 and therefore may be further used as anticancer agents.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-60-37
WGK Germany  3
HazardClass  IRRITANT
HS Code  29349990

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