A3591412
Diethyl 5-Amino-3-methyl-2,4-thiophenedicarboxylate , >98.0%(GC) , 4815-30-9
CAS NO.:4815-30-9
Empirical Formula: C11H15NO4S
Molecular Weight: 257.31
MDL number: MFCD00005450
EINECS: 225-388-0
Pack Size | Price | Stock | Quantity |
5G | RMB140.00 | In Stock |
|
25G | RMB450.40 | In Stock |
|
100G | RMB1481.60 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 105-108 °C(lit.) |
Boiling point: | 372.6±37.0 °C(Predicted) |
Density | 1.3137 (rough estimate) |
refractive index | 1.5500 (estimate) |
pka | -0.53±0.10(Predicted) |
form | Crystalline Powder |
color | Slightly yellow to beige-yellow |
CAS DataBase Reference | 4815-30-9(CAS DataBase Reference) |
Description and Uses
Diethyl 5-Amino-3-methylthiophene-2,4-dicarboxylate is used as a reagent in the synthesis of novel pyrazolo-pyrimidinones as dipeptidyl peptidase IV (DPP-IV) inhibitors in diabetes. It is also used in the synthesis of N-phenylthieno[2,3-d]pyrimidin-4-amines which act as inhibitors of fibroblast grow factor receptor 1 and therefore may be further used as anticancer agents.
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H315-H319-H335 |
Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 26-36-60-37 |
WGK Germany | 3 |
HazardClass | IRRITANT |
HS Code | 29349990 |