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A3526912

Dicoumarol , ≥98.0% , 66-76-2

Synonym(s):
3,3ʹ-Methylenebis(4-hydroxycoumarin), Bishydroxycoumarin, Dicumarol;Bishydroxycoumarin;Dicoumarol;Dicoumarol - CAS 66-76-2 - Calbiochem;Dicumarol

CAS NO.:66-76-2

Empirical Formula: C19H12O6

Molecular Weight: 336.3

MDL number: MFCD00006857

EINECS: 200-632-9

Pack Size Price Stock Quantity
1G RMB63.20 In Stock
5g RMB207.20 In Stock
25G RMB719.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 290-292 °C(lit.)
Boiling point: 392.79°C (rough estimate)
Density  1.2864 (rough estimate)
refractive index  1.4450 (estimate)
storage temp.  Sealed in dry,Room Temperature
solubility  DMSO:3.06(Max Conc. mg/mL);9.1(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);1.49(Max Conc. mM)
DMF:1.25(Max Conc. mg/mL);3.72(Max Conc. mM)
Water:50.0(Max Conc. mg/mL);148.68(Max Conc. mM)
pka 4.20±1.00(Predicted)
form  Fine Crystalline Powder
color  White
Water Solubility  Soluble in aqueous alkaline solutions, organic bases, 0.1 N NaOH (15 mg/ml), Pyridine (50 mg/ml), chloroform (slightly soluble), and benzene (slightly soluble). Insoluble in water, and alcohols.
Merck  14,3090

Description and Uses

The plants containing dicoumarol mainly include red carnation grass (Trifolium pratense L., hongchezhoucao), rotten alfalfa (Medicago sativa L., zimuxu), rotten white vanilla rhinoceros (Melilotus albus Desr., baixiangcaomuxi), and other plants in Leguminosae.

This drug is used for preventing and treating thrombosis, thrombophlebitis, thromboemolium, and for preventing thrombo-formation in post-operational periods.

Safety

Symbol(GHS) 
GHS06,GHS08,GHS09
Signal word  Danger
Hazard statements  H301-H372-H411
Precautionary statements  P260-P264-P270-P273-P301+P310-P314
Hazard Codes  T,N
Risk Statements  22-48/25-51/53
Safety Statements  37-45-61
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  GN7875000
TSCA  Yes
HazardClass  6.1(b)
PackingGroup  III
HS Code  29322985
Toxicity LD50 orally in rats: 541.6 mg/kg (Rose)

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