Home Categories Pharmaceutical intermediates 6,6'-Dithiodinicotinic Acid
A3479812

6,6'-Dithiodinicotinic Acid , >98.0%(HPLC) , 15658-35-2

Synonym(s):
Bis[3-carboxypyridine] 6,6′-disulfide

CAS NO.:15658-35-2

Empirical Formula: C12H8N2O4S2

Molecular Weight: 308.33

MDL number: MFCD00006454

EINECS: 239-729-6

Pack Size Price Stock Quantity
1G RMB239.20 In Stock
5G RMB1039.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 263-265 °C(lit.)
Boiling point: 584.2±50.0 °C(Predicted)
Density  1.66±0.1 g/cm3(Predicted)
storage temp.  Sealed in dry,Room Temperature
pka 2.82±0.10(Predicted)
form  powder to crystal
color  White to Light yellow
Stability: Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference 15658-35-2(CAS DataBase Reference)

Description and Uses

6,6′-Dithiodinicotinic acid may be employed as:

  • specific thiol blocker to investigate the radioprotective effect of mercaptoethylamine on the thiol level of the outer cell membrane of the Ehrlich ascites tumor cells
  • modifier to investigate the polar microenvironment around the reactive Cys283 of rabbit muscle creatine kinase
  • dipyridyl-dithio substrate to evaluate the protein disulfide-thiol interchange activity of the auxin stimulated NADH: protein disulfide reductase (NADH oxidase) of soybean plasma membranes
  • water-soluble reagent in a study for introducing, in buffered saline, a reactive sulfhydryl group on water-soluble molecules bearing an alkyl-amino group
  • chromogen for sulfhydryl groups in the Ellman method for cholinesterase determinations
  • spectrophotometric determination of thiols and of total glutathione in human blood

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26
WGK Germany  3
RTECS  US5684700
HS Code  2933399990

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