A3325312
Deflazacort , ≥98%(HPLC) , 14484-47-0
Synonym(s):
(11β,16β)-21-(acetyloxy)-11-hydroxy-2′-methyl-5′H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione;11β,21-dihydroxy-2′-methyl-5′βH-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione 2′-acetate;azacort;oxazacort;pregna-1,4-diene-11β,21-diol-3,20-dione[17α,16α-d]-2′-methyloxazoline 21-acetate
CAS NO.：14484-47-0
Empirical Formula: C25H31NO6
Molecular Weight: 441.52
MDL number: MFCD00866106
EINECS: 238-483-7
| Pack Size | Price | Stock | Quantity |
| 1G | RMB530.40 | In Stock |
|
| 5G | RMB1822.40 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 255-256.5°C |
| alpha | D +62.3° (c = 0.5 in chloroform) |
| Boiling point: | 595.4±50.0 °C(Predicted) |
| Density | 1.41 |
| storage temp. | 2-8°C |
| solubility | DMSO: ≥20mg/mL |
| pka | 14.30±0.70(Predicted) |
| form | powder |
| color | white to tan |
| Merck | 14,2862 |
| InChIKey | FBHSPRKOSMHSIF-UBRVQRTASA-N |
| SMILES | C12(C(COC(C)=O)=O)[C@]3(C)C(C4C([C@H](C3)O)[C@]3(C)C(=CC(C=C3)=O)CC4)CC1OC(C)=N2 |
Description and Uses
Deflazacort is an antiinflammatory treatment of rheumatoid arthritis. Its antirheumatic potency i s similar to that of prednisone, while its hyperglycernic and calcium depleting effects are reportedly less.
A systemic corticosteroid. A derivative of prednisolone. Used for rheumatoid arthritis and lupus
Safety
| Symbol(GHS) |  GHS08 |
| Signal word | Danger |
| Hazard statements | H360-H373 |
| Precautionary statements | P260-P314-P501 |
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| RTECS | TU4157050 |
| HS Code | 29349990 |
| Toxicity | LD50 orally in mice: 5200 mg/kg (Schiatti) |
