4-Dimethylaminopyridine , 99% , 1122-58-3

Synonym(s):
DMAP;4-Dimethylaminopyridine;4-(Dimethylamino)pyridine;Valaciclovir Related Compound G (USP);DMAP solution

CAS NO.：1122-58-3

Empirical Formula: C7H10N2

Molecular Weight: 122.17

MDL number: MFCD00006418

EINECS: 214-353-5

PRODUCT Properties

• Melting point: 112 °C
• Boiling point: 162 °C
• Density: 0.906 g/mL at 25 °C
• vapor pressure: 0.169 hPa at 20 °C
• refractive index: n20/D 1.431
• Flash point: 110 °C
• storage temp.: Store below +30°C.
• solubility: methanol: 50 mg/mL, clear
• form: prilled
• pka: pKa (20°): 9.7
• color: off-white to yellow
• PH: 11 (60g/l, H2O, 20℃)
• Odor: characteristic odor
• PH Range: 9.7 (10% aq soln)
• Water Solubility: 76 g/L (25 ºC)
• Merck: 14,3389
• BRN: 110354
• Stability: Stable. Incompatible with acids, oxidizing agents.
• LogP: 1.34 at 25℃
• CAS DataBase Reference: 1122-58-3(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Pyridinamine, N,N-dimethyl-(1122-58-3)
• EPA Substance Registry System: 4-(Dimethylamino)pyridine (1122-58-3)

Description and Uses

DMAP is a useful highly basic nucleophilic catalyst for a variety of reactions such as esterifications with anhydrides, the Baylis-Hillman reaction, hydrosilylations, tritylation, the Steglich rearrangement.

Safety

• Symbol(GHS): GHS05,GHS06,GHS08,GHS09
• Signal word: Danger
• Hazard statements: H301+H331-H310-H315-H318-H370-H411
• Precautionary statements: P262-P273-P280-P301+P310-P302+P352+P310-P305+P351+P338
• Hazard Codes: T,C,T+,Xn,F
• Risk Statements: 25-34-24/25-36/37/38-27-36-24-20-61-40-23/24/25-67-66-21/22-11-36/37-22-19
• Safety Statements: 36/37/39-45-28A-26-28-36/37-53-27-22-16
• RIDADR: UN 2811 6.1/PG 2
• WGK Germany: 3
• RTECS: US8400000
• Autoignition Temperature: 420 °C
• Hazard Note: Toxic/Corrosive
• TSCA: T
• HazardClass: 8
• PackingGroup: II
• HS Code: 29333999
• Toxicity: LD50 orally in Rabbit: 140 mg/kg LD50 dermal Rabbit 90 mg/kg