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A3159512

2,5-Dimethylpyrazine , 98% , 123-32-0

CAS NO.:123-32-0

Empirical Formula: C6H8N2

Molecular Weight: 108.14

MDL number: MFCD00006147

EINECS: 204-618-3

Pack Size Price Stock Quantity
25ML RMB46.40 In Stock
100ML RMB193.60 In Stock
500ML RMB733.60 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 15°C
Boiling point: 155 °C (lit.)
Density  0.99 g/mL at 25 °C (lit.)
FEMA  3272 | 2,5-DIMETHYLPYRAZINE
refractive index  n20/D 1.502(lit.)
Flash point: 147 °F
storage temp.  Inert atmosphere,Room Temperature
solubility  Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form  Liquid
pka 2.21±0.10(Predicted)
Specific Gravity 0.990
color  Clear colorless to pale yellow
PH 7 (H2O)
Odor at 0.10 % in dipropylene glycol. nutty roasted baked potato
Odor Type chocolate
Sensitive  Hygroscopic
JECFA Number 766
BRN  107052
Dielectric constant 2.4399999999999999
LogP 0.64
CAS DataBase Reference 123-32-0(CAS DataBase Reference)
NIST Chemistry Reference Pyrazine, 2,5-dimethyl-(123-32-0)
EPA Substance Registry System Pyrazine, 2,5-dimethyl- (123-32-0)

Description and Uses

2,5-Dimethylpyrazine is used as a reagent in the synthesis of bone-targeted proteasome inhibitors for multiple myeloma (MM). 2,5-Dimethylpyrazine is also used in the preparation of 3-Methyl-2,5-bis-(2-hydroxyethyl)pyrazine (M295340); a degredation product of Clavulanic Acid (C563750) which is a β-lactamase inhibitor, typically added to amoxicillin to increase its effectiveness.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P301+P312+P330
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38-R22
Safety Statements  26-36
RIDADR  NA 1993 / PGIII
WGK Germany  3
RTECS  UQ2800000
Hazard Note  Irritant
TSCA  Yes
HS Code  29339990

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