A3147012
DL-Dithiothreitol , Used for molecular biology, ≥99% , 3483-12-3
Synonym(s):
DTT;1,4-Dithiothreitol;Cleland’s reagent;Dithiothreitol, DTT;(±)-threo-1,4-Dimercapto-2,3-butanediol solution
CAS NO.：3483-12-3
Empirical Formula: C4H10O2S2
Molecular Weight: 154.25
MDL number: MFCD00004877
EINECS: 222-468-7
| Pack Size | Price | Stock | Quantity |
| 1G | RMB45.60 | In Stock |
|
| 5G | RMB159.20 | In Stock |
|
| 25G | RMB719.20 | In Stock |
|
| 100g | RMB2159.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 41-44 °C(lit.) |
| Boiling point: | 125 °C |
| alpha | -0.2～+0.2°(20℃/D)(c=5,H2O) |
| Density | 1.04 g/mL at 20 °C |
| vapor density | 5.3 (vs air) |
| vapor pressure | 0.019-0.29Pa at 20-50℃ |
| refractive index | 1.5200 (estimate) |
| Flash point: | >230 °F |
| storage temp. | -20°C (or 4°C short term). |
| solubility | H2O: 50 mg/mL, clear, colorless |
| pka | pK1:8.9 (25°C) |
| form | Powder |
| color | White |
| PH | 4.0-6.0 (20-25℃, 0.1m in H2O) |
| Odor | Unpleasant Odor |
| PH Range | 4 - 6 at 15,4 g/l at 25 °C |
| Water Solubility | freely soluble |
| λmax | λ: 260 nm Amax: 0.400 λ: 280 nm Amax: 0.100 |
| Sensitive | Air Sensitive |
| Merck | 14,3376 |
| BRN | 1719757 |
| Stability: | Stability Stable, but heat sensitive. Incompatible with strong oxidizing agents. Keep frozen at -20 to -10 C. |
| InChIKey | VHJLVAABSRFDPM-UHFFFAOYSA-N |
| LogP | 0.07 at 25℃ and pH5 |
| CAS DataBase Reference | 3483-12-3(CAS DataBase Reference) |
| NIST Chemistry Reference | 2,3-Butanediol, 1,4-dimercapto-, (r*,r*)-(3483-12-3) |
| EPA Substance Registry System | 1,4-Dithiothreitol (3483-12-3) |
Description and Uses
Dithiothreitol is a redox reagent commonly used as a reducing agent for thiolated DNA. Dithiothreitol is also used to reduce the disulfide bonds of proteins.
Safety
| Symbol(GHS) |   GHS05,GHS07 |
| Signal word | Danger |
| Hazard statements | H302-H315-H318 |
| Precautionary statements | P264-P270-P280-P301+P312-P302+P352-P305+P351+P338 |
| Hazard Codes | Xn |
| Risk Statements | 25-36/37/38-22-20/21/22 |
| Safety Statements | 26-45-37/39-36 |
| RIDADR | UN 3335 |
| WGK Germany | 3 |
| RTECS | EK1610000 |
| F | 3-10-16-23 |
| TSCA | Yes |
| HS Code | 29309099 |
| Hazardous Substances Data | 3483-12-3(Hazardous Substances Data) |
