2-Mercaptoethanol , Biotechnology , 60-24-2
Synonym(s):
β-Mercaptoethanol;2-Hydroxyethylmercaptan;2-Mercaptoethanol;BME;Thioethylene glycol
CAS NO.：60-24-2
Empirical Formula: C2H6OS
Molecular Weight: 78.13
MDL number: MFCD00004890
EINECS: 200-464-6
PRODUCT Properties
| Melting point: | -100 °C |
| Boiling point: | 157 °C (lit.) |
| Density | 1.114 g/mL at 25 °C (lit.) |
| vapor density | 2.69 (vs air) |
| vapor pressure | 1 mm Hg ( 20 °C) |
| refractive index | n |
| FEMA | 4582 | 2-HYDROXYETHANETHIOL |
| Flash point: | 165 °F |
| storage temp. | Store below +30°C. |
| solubility | H2O: 1 mL/mL |
| form | liquid |
| pka | 9.72(at 25℃) |
| color | Clear colorless to slightly yellow |
| Specific Gravity | 1.119 (20/4℃) |
| Odor | Disagreeable odor |
| PH Range | 4.5 - 6 at 500 g/l at 20 °C |
| PH | 4.5-6 (500g/l, H2O, 20℃) |
| explosive limit | 2.3-18%(V) |
| Water Solubility | soluble |
| FreezingPoint | <100℃ |
| Sensitive | Air Sensitive & Hygroscopic |
| λmax | λ: 260 nm Amax: 1.5 λ: 280 nm Amax: 0.3 |
| JECFA Number | 1925 |
| Merck | 14,5869 |
| BRN | 773648 |
| Stability: | Air Sensitive |
| LogP | -0.20 |
| CAS DataBase Reference | 60-24-2(CAS DataBase Reference) |
| NIST Chemistry Reference | Ethanol, 2-mercapto-(60-24-2) |
| EPA Substance Registry System | 2-Mercaptoethanol (60-24-2) |
Description and Uses
2-Mercaptoethanol is used in the preparation of nano-graphene for cellular imaging and drug delivery as well as multifunctional polymeric micelle. It acts as a reducing agent used in electrophoresis, amino acid detection, and distinguishing ssDNA/dsDNA. It is also employed as a standard buffer. It is also used in the preparation of PVC heat stabilizers and as a chain transfer agent in the manufacture of PVC. Further, it is used in some RNA isolation procedures to eliminate ribonuclease. It is utilized as a corrosion inhibitor and ore floatation agent. In biochemistry, it is useful to study the activity of the immune system. Solubilizes proteins by reducing disulfide linkages.
Safety
| Symbol(GHS) |     GHS05,GHS06,GHS08,GHS09 |
| Signal word | Danger |
| Hazard statements | H301+H331-H310-H315-H317-H318-H361d-H373-H410 |
| Precautionary statements | P273-P280-P301+P310-P302+P352+P310-P304+P340+P311-P305+P351+P338 |
| Hazard Codes | T,N |
| Risk Statements | 20/22-24-34-51/53-36/37/38-22-23/24/25-50/53-48/22-43-41-38 |
| Safety Statements | 26-36/37/39-45-61-29-23-27-60 |
| RIDADR | UN 2966 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS | KL5600000 |
| F | 3-10-13-23 |
| Autoignition Temperature | 295 °C |
| TSCA | Yes |
| HazardClass | 6.1 |
| PackingGroup | II |
| HS Code | 29309070 |
| Hazardous Substances Data | 60-24-2(Hazardous Substances Data) |
