Home Categories Food Additives 2-Mercaptoethanol
A1157550

2-Mercaptoethanol , Biotechnology , 60-24-2

Synonym(s):
β-Mercaptoethanol;2-Hydroxyethylmercaptan;2-Mercaptoethanol;BME;Thioethylene glycol

CAS NO.:60-24-2

Empirical Formula: C2H6OS

Molecular Weight: 78.13

MDL number: MFCD00004890

EINECS: 200-464-6

Update time: 2022-07-08

PRODUCT Properties

Melting point: -100 °C
Boiling point: 157 °C (lit.)
Density  1.114 g/mL at 25 °C (lit.)
vapor density  2.69 (vs air)
vapor pressure  1 mm Hg ( 20 °C)
refractive index  n20/D 1.500(lit.)
FEMA  4582 | 2-HYDROXYETHANETHIOL
Flash point: 165 °F
storage temp.  Store below +30°C.
solubility  H2O: 1 mL/mL
form  liquid
pka 9.72(at 25℃)
color  Clear colorless to slightly yellow
Specific Gravity 1.119 (20/4℃)
Odor Disagreeable odor
PH Range 4.5 - 6 at 500 g/l at 20 °C
PH 4.5-6 (500g/l, H2O, 20℃)
explosive limit 2.3-18%(V)
Water Solubility  soluble
FreezingPoint  <100℃
Sensitive  Air Sensitive & Hygroscopic
λmax λ: 260 nm Amax: 1.5
λ: 280 nm Amax: 0.3
JECFA Number 1925
Merck  14,5869
BRN  773648
Stability: Air Sensitive
LogP -0.20

Description and Uses

2-Mercaptoethanol is used in the preparation of nano-graphene for cellular imaging and drug delivery as well as multifunctional polymeric micelle. It acts as a reducing agent used in electrophoresis, amino acid detection, and distinguishing ssDNA/dsDNA. It is also employed as a standard buffer. It is also used in the preparation of PVC heat stabilizers and as a chain transfer agent in the manufacture of PVC. Further, it is used in some RNA isolation procedures to eliminate ribonuclease. It is utilized as a corrosion inhibitor and ore floatation agent. In biochemistry, it is useful to study the activity of the immune system. Solubilizes proteins by reducing disulfide linkages.

Safety

Symbol(GHS) 
GHS05,GHS06,GHS08,GHS09
Signal word  Danger
Hazard statements  H301+H331-H310-H315-H317-H318-H361d-H373-H410
Precautionary statements  P273-P280-P301+P310-P302+P352+P310-P304+P340+P311-P305+P351+P338
Hazard Codes  T,N
Risk Statements  20/22-24-34-51/53-36/37/38-22-23/24/25-50/53-48/22-43-41-38
Safety Statements  26-36/37/39-45-61-29-23-27-60
RIDADR  UN 2966 6.1/PG 2
WGK Germany  3
RTECS  KL5600000
3-10-13-23
Autoignition Temperature 295 °C
TSCA  Yes
HazardClass  6.1
PackingGroup  II
HS Code  29309070

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