2-Deoxy-D-Ribose , 98% , 533-67-5

Synonym(s):
2-Deoxy-D-arabinose;2-Deoxy-D-erythropentose;Thyminose

CAS NO.：533-67-5

Empirical Formula: C5H10O4

Molecular Weight: 134.13

MDL number: MFCD00135904

EINECS: 208-573-0

PRODUCT Properties

• Melting point: 89-90 °C(lit.)
• alpha: -57 º (c=1, H2O, 24hr)
• Boiling point: 167.23°C (rough estimate)
• Density: 1.0590 (rough estimate)
• refractive index: -56 ° (C=1, H2O)
• storage temp.: Keep in dark place,Inert atmosphere,Room temperature
• solubility: DMSO (Slightly), Methanol (Slightly), Water (Slightly, Sonicated)
• form: Crystalline Powder
• pka: 12.61(at 25℃)
• color: White to slightly yellow
• optical activity: [α]22/D 59°, c = 1 in H2O
• Water Solubility: soluble
• Sensitive: Hygroscopic
• Merck: 14,2908
• BRN: 1721978
• Stability: Hygroscopic
• InChIKey: ASJSAQIRZKANQN-CRCLSJGQSA-N

Description and Uses

2-deoxy-D-Ribose is a reducing sugar formed as a degradation product during metabolism of thymidine by thymidine phosphorylase. It increases levels of reactive oxygen species (ROS) in HL-60 human leukemia cells when used at a concentration of 15 mM. 2-deoxy-D-Ribose (10 μM) induces tubulogenesis and migration of bovine aortic endothelial (BAE) cells. Topical administration of 2-deoxy-D-ribose increases blood vessel formation and accelerates wound healing in a rat full-thickness cutaneous wound model.

2-Deoxy-D-ribose is used as a precursor to deoxyribonucleic acid. It induces apoptosis by inhibiting the synthesis and increasing the efflux of glutathione. Further, it is used in the synthesis of optically active dipyrrolyl alkanols from pyrroles on the surface of montmorillonite KSF clay.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H332-H335
• Precautionary statements: P261-P280-P305+P351+P338
• Hazard Codes: Xn,Xi
• Risk Statements: 20/21/22-36/37/38
• Safety Statements: 24/25-37/39-36-26
• WGK Germany: 3
• RTECS: SB7230000
• F: 3-10
• TSCA: Yes
• HS Code: 29400000