A2685912
4-<WBR>Chlorophenylboronic acid pinacol ester , 97% , 195062-61-4
Synonym(s):
4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)chlorobenzene
CAS NO.：195062-61-4
Empirical Formula: C12H16BClO2
Molecular Weight: 238.52
MDL number: MFCD05663875
| Pack Size | Price | Stock | Quantity |
| 1G | RMB29.60 | In Stock |
|
| 5G | RMB88.00 | In Stock |
|
| 10G | RMB216.00 | In Stock |
|
| 25G | RMB435.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 50-55 °C(lit.) |
| Boiling point: | 308.7±25.0 °C(Predicted) |
| Density | 1.10±0.1 g/cm3(Predicted) |
| Flash point: | >230 °F |
| storage temp. | 2-8°C |
| solubility | soluble in Methanol |
| form | Solid |
| color | White to pale brown |
| InChIKey | NYARTXMDWRAVIX-UHFFFAOYSA-N |
| CAS DataBase Reference | 195062-61-4 |
Description and Uses
4-Chlorophenylboronic acid pinacol ester can be used as a reagent in Suzuki-Miyaura cross-coupling reaction to form C-C bonds by reacting with different aryl halides over palladium catalysts.
It can also be used as a reactant:
- To prepare 2-(4-chlorophenyl)-4H-chromen-4-one by treating with 4-chromanone via one-pot palladium-catalyzed dehydrogenation and oxidative boron-Heck coupling reaction.
- In the ligand-enabled C-H bond activation reaction in the presence of a palladium catalyst.
- To synthesize biaryl amides via Cu-catalyzed C-H bond coupling of aryl arylamides.
