Home Categories Pharmaceutical intermediates 4-Chloro-6,7-dimethoxyquinoline
A2546112

4-Chloro-6,7-dimethoxyquinoline , ≥98.0% , 35654-56-9

CAS NO.:35654-56-9

Empirical Formula: C11H10ClNO2

Molecular Weight: 223.66

MDL number: MFCD07778437

EINECS: 676-028-8

Pack Size Price Stock Quantity
1g RMB24.00 In Stock
5G RMB87.20 In Stock
25G RMB308.00 In Stock
100g RMB1160.80 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 132.0 to 136.0 °C
Boiling point: 325.2±37.0 °C(Predicted)
Density  1.265±0.06 g/cm3(Predicted)
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
solubility  DMSO (Slightly), Methanol (Slightly)
form  Solid
pka 3.95±0.30(Predicted)
color  Pale Brown to Light Brown
InChI InChI=1S/C11H10ClNO2/c1-14-10-5-7-8(12)3-4-13-9(7)6-11(10)15-2/h3-6H,1-2H3
InChIKey WRVHQEYBCDPZEU-UHFFFAOYSA-N
SMILES N1C2C(=CC(OC)=C(OC)C=2)C(Cl)=CC=1

Description and Uses

4-Chloro-6,7-dimethoxyquinoline, can be used as an intermediate for the synthesis of various pharmaceutical and biologically active compounds. It is used for the preparation of Tivozanib (T447205), and Cabozantinib (C051500), acting as anticancer agents.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H319-H315-H335
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
Hazard Codes  T
Risk Statements  25
Safety Statements  45-24/25
RIDADR  UN2811
HazardClass  IRRITANT
HS Code  29334900

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