Home Categories Analytical Chemistry Cyclobenzaprine hydrochloride
A2501112

Cyclobenzaprine hydrochloride , 98% , 6202-23-9

Synonym(s):
5-(3-Dimethylaminopropylidene)dibenzo[a,e]cycloheptatriene hydrochloride;Cyclobenzaprine hydrochloride

CAS NO.:6202-23-9

Empirical Formula: C20H22ClN

Molecular Weight: 311.85

MDL number: MFCD00079039

EINECS: 228-264-4

Pack Size Price Stock Quantity
1G RMB263.20 In Stock
5G RMB820.80 In Stock
25G RMB3519.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 216-2180C
Flash point: 9℃
storage temp.  Inert atmosphere,Room Temperature
Water Solubility  Completely soluble in water
solubility  ≥15.59 mg/mL in DMSO; ≥5.32 mg/mL in EtOH; ≥54.3 mg/mL in H2O
form  Solid
color  White to Almost white
λmax 290nm(lit.)
Merck  14,2713
InChIKey VXEAYBOGHINOKW-UHFFFAOYSA-N

Description and Uses

Cyclobenzaprine is a skeletal muscle relaxant that also has sedative properties. It has been shown to antagonize muscarinic receptors (Kis = 25, 60, and 6 nM for M1, M2, and M3, respectively), serotonin 5-HT2 receptors (Kis = 56 and 330 nM for 5-HT2C and 5-HT2B, respectively), and histamine H1 receptor (IC50 = 20 nM).

Cyclobenzaprine hydrochloride has been used to study its effect on the muscles of dystrophin-deficient mdx5Cv mice.

Safety

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H301-H312+H332
Precautionary statements  P280-P301+P310+P330-P302+P352+P312-P304+P340+P312
Hazard Codes  Xn,T,F
Risk Statements  20/21/22-39/23/24/25-23/24/25-11
Safety Statements  36-45-36/37-16-7
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  HP0875000
HazardClass  6.1(b)
PackingGroup  III
HS Code  29214990
Toxicity LD50 in mice (mg/kg): 35 i.v., 250 orally (Metysova)

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