Cefoperazone , ≥98% , 62893-19-0

CAS NO.：62893-19-0

Empirical Formula: C25H27N9O8S2

Molecular Weight: 645.67

MDL number: MFCD00865067

EINECS: 263-749-4

PRODUCT Properties

• Melting point: 169-171 C
• Density: 1.77±0.1 g/cm3(Predicted)
• storage temp.: 2-8°C
• solubility: DMSO (Slightly, Sonicated), Methanol (Slightly, Heated, Sonicated)
• form: Solid
• pka: pKa 2.6 (Uncertain)
• color: White to Off-White
• Merck: 14,1930
• InChIKey: GCFBRXLSHGKWDP-XCGNWRKASA-N
• SMILES: N12[C@@]([H])([C@H](NC([C@H](NC(N3CCN(CC)C(=O)C3=O)=O)C3=CC=C(O)C=C3)=O)C1=O)SCC(CSC1N(C)N=NN=1)=C2C(O)=O

Description and Uses

Cefoperazone has a C-7 side chain reminiscent of piperacillin's and also possesses the C-3 side chain (MTT ) that often is associated with the bleeding and alcohol intolerance problems among patients taking cephalosporins. Its useful activity against pseudomonads partly compensates for this, although it is not potent enough to be used as a single agent against this difficult pathogen. The C-7 side chain does not convey sufficient resistance to many β-lactamases, although the addition of clavulanic acid or sulbactam would presumably help.

Antibacterial.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P305+P351+P338
• Hazard Codes: Xn
• Risk Statements: 20/21/22-36/37/38
• Safety Statements: 26-36
• RTECS: XI0373900
• HS Code: 29419000