A2458812
Cyclophosphamide , ≥98% , 50-18-0
Synonym(s):
2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide;Cyclophosphamide monohydrate;Cytoxan
CAS NO.:50-18-0
Empirical Formula: C7H15Cl2N2O2P
Molecular Weight: 261.09
MDL number: MFCD00005978
EINECS: 200-015-4
Pack Size | Price | Stock | Quantity |
25mg | RMB158.40 | In Stock |
|
100MG | RMB472.00 | In Stock |
|
500MG | RMB1584.00 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 41-45°C |
Boiling point: | 336.1±52.0 °C(Predicted) |
Density | 1.33±0.1 g/cm3(Predicted) |
storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
solubility | ≥11.85 mg/mL in H2O with gentle warming and ultrasonic; ≥13.05 mg/mL in DMSO; ≥50.8 mg/mL in EtOH |
pka | 2.84±0.20(Predicted) |
form | solid |
color | White to off-white |
Water Solubility | Soluble. 1-5 g/100 mL at 23 ºC |
BCS Class | 1,3 |
Stability: | Stable, but light sensitive. Incompatible with oxidizing agents. |
CAS DataBase Reference | 50-18-0(CAS DataBase Reference) |
IARC | 1 (Vol. 26, Sup 7, 100A) 2012 |
NIST Chemistry Reference | 2-[Bis(2-chloroethylamino)]-tetrahydro-2h-1,3,2-oxazaphosphorine-2-oxide(50-18-0) |
EPA Substance Registry System | Cyclophosphamide (50-18-0) |
Description and Uses
An anti-proliferative agent that regulates Bax and Bcl-2 expression.
Safety
Symbol(GHS) | GHS08,GHS06 |
Signal word | Danger |
Hazard statements | H301-H360-H340-H350 |
Precautionary statements | P264-P270-P301+P310-P321-P330-P405-P501 |
Safety Statements | 22-24/25 |
RIDADR | UN 1851 |
HazardClass | 6.1(b) |
PackingGroup | III |
Hazardous Substances Data | 50-18-0(Hazardous Substances Data) |
Toxicity | LD50 oral in rat: 100mg/kg |