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A2458812

Cyclophosphamide , ≥98% , 50-18-0

Synonym(s):
2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide;Cyclophosphamide monohydrate;Cytoxan

CAS NO.:50-18-0

Empirical Formula: C7H15Cl2N2O2P

Molecular Weight: 261.09

MDL number: MFCD00005978

EINECS: 200-015-4

Pack Size Price Stock Quantity
25mg RMB158.40 In Stock
100MG RMB472.00 In Stock
500MG RMB1584.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 41-45°C
Boiling point: 336.1±52.0 °C(Predicted)
Density  1.33±0.1 g/cm3(Predicted)
storage temp.  Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility  ≥11.85 mg/mL in H2O with gentle warming and ultrasonic; ≥13.05 mg/mL in DMSO; ≥50.8 mg/mL in EtOH
pka 2.84±0.20(Predicted)
form  solid
color  White to off-white
Water Solubility  Soluble. 1-5 g/100 mL at 23 ºC
BCS Class 1,3
Stability: Stable, but light sensitive. Incompatible with oxidizing agents.
CAS DataBase Reference 50-18-0(CAS DataBase Reference)
IARC 1 (Vol. 26, Sup 7, 100A) 2012
NIST Chemistry Reference 2-[Bis(2-chloroethylamino)]-tetrahydro-2h-1,3,2-oxazaphosphorine-2-oxide(50-18-0)
EPA Substance Registry System Cyclophosphamide (50-18-0)

Description and Uses

An anti-proliferative agent that regulates Bax and Bcl-2 expression.

Safety

Symbol(GHS) 
GHS08,GHS06
Signal word  Danger
Hazard statements  H301-H360-H340-H350
Precautionary statements  P264-P270-P301+P310-P321-P330-P405-P501
Safety Statements  22-24/25
RIDADR  UN 1851
HazardClass  6.1(b)
PackingGroup  III
Hazardous Substances Data 50-18-0(Hazardous Substances Data)
Toxicity LD50 oral in rat: 100mg/kg

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