A2452612
2-Chloro-6-fluorobenzoic Acid , ≥98.0% , 434-75-3
CAS NO.:434-75-3
Empirical Formula: C7H4ClFO2
Molecular Weight: 174.56
MDL number: MFCD00002417
EINECS: 207-105-2
Pack Size | Price | Stock | Quantity |
5G | RMB27.20 | In Stock |
|
25G | RMB65.60 | In Stock |
|
100G | RMB172.00 | In Stock |
|
500G | RMB592.00 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 155-157 °C(lit.) |
Boiling point: | 263.7±20.0 °C(Predicted) |
Density | 1.4016 (estimate) |
storage temp. | Sealed in dry,Room Temperature |
pka | 2.04±0.10(Predicted) |
form | powder to crystal |
color | White to Gray to Brown |
BRN | 973857 |
InChIKey | XNTIGDVFBDJLTQ-UHFFFAOYSA-N |
CAS DataBase Reference | 434-75-3(CAS DataBase Reference) |
NIST Chemistry Reference | 2-Chloro-6-fluorobenzoic acid(434-75-3) |
Description and Uses
2-Chloro-6-fluorobenzoic Acid is a versatile reactant used in the synthesis of biaryls via decarboxylative Pd-catalyzed cross-coupling with aryl iodides. Also used in the preparation of fluorinated biaryls and heterobiaryls using copper catalyzed decarboxylative cross-coupling of aryl and heteroalyl iodides or bromides with potassium polyfluorobenzoates.
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H315-H319-H335 |
Precautionary statements | P280a-P304+P340-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P305+P351+P338 |
Hazard Codes | Xi,Xn |
Risk Statements | 36/37/38-37/38-36-20/21/22 |
Safety Statements | 26-36-37/39 |
WGK Germany | 3 |
HazardClass | IRRITANT |
HS Code | 29163900 |