2-Chloro-3-methylpyridine , 98% , 18368-76-8

CAS NO.：18368-76-8

Empirical Formula: C6H6ClN

Molecular Weight: 127.57

MDL number: MFCD00234177

EINECS: 242-242-1

PRODUCT Properties

• Melting point: 193 °C
• Boiling point: 192-193 °C/751 mmHg (lit.)
• Density: 1.17 g/mL at 25 °C (lit.)
• refractive index: n20/D 1.533(lit.)
• Flash point: 175 °F
• storage temp.: Inert atmosphere,Room Temperature
• pka: 0.75±0.10(Predicted)
• form: Liquid
• color: Colorless to light yellow
• Specific Gravity: 1.170
• BRN: 107895
• InChI: InChI=1S/C6H6ClN/c1-5-3-2-4-8-6(5)7/h2-4H,1H3
• InChIKey: RKVUCIFREKHYTL-UHFFFAOYSA-N
• SMILES: C1(Cl)=NC=CC=C1C

Description and Uses

2-Chloro-3-methylpyridine is an intermediate for many medicines and pesticides, such as fluazifop, nicosulfuron, and fluazifop. Moreover, with the gradual promotion of these new high-efficiency and low-toxic heterocyclic pesticides, 2-chloro-3-methylpyridine is increasing. The industrial method for preparing 2-chloro-3-methylpyridine is to obtain it by site-specific chlorination of 3-methylpyridine. First, 3-methylpyridine is epoxidized and then chlorinated. The main chlorinated 3-methylpyridine is a mixture of 2-chloro-3-methylpyridine and 2-chloro-5-methylpyridine, of which 2-chloro-3-methylpyridine accounts for 20% (mass).

2-Chloro-3-methylpyridine is an active ingredient and a major constituent of imidaclopide, a systemic insecticide that acts as insect neurotoxin and belongs to a class of chemical called the neonicotinoids.

Safety

• Symbol(GHS): GHS07,GHS06
• Signal word: Warning
• Hazard statements: H227-H302+H312+H332-H302-H312-H331-H315-H319-H335
• Precautionary statements: P210e-P405-P501a-P210-P261-P264-P270-P271-P280-P301+P312+P330-P302+P352+P312+P362+P364-P304+P340+P312-P305+P351+P338+P337+P313-P403+P235-P501-P305+P351+P338
• Hazard Codes: Xi,Xn
• Risk Statements: 36/37/38-20/21/22
• Safety Statements: 26-36-36/37/39
• RIDADR: 2810
• WGK Germany: 3
• HazardClass: 6.1
• PackingGroup: III
• HS Code: 29333990