Home Categories Pharmaceutical intermediates 2-Chloro-5-iodopyridine
A2401712

2-Chloro-5-iodopyridine , 98% , 69045-79-0

CAS NO.:69045-79-0

Empirical Formula: C5H3ClIN

Molecular Weight: 239.44

MDL number: MFCD01863635

EINECS: 627-359-1

Pack Size Price Stock Quantity
1G RMB23.20 In Stock
5G RMB56.80 In Stock
25G RMB224.80 In Stock
100G RMB895.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 95-98 °C (lit.)
Boiling point: 253.2±20.0 °C(Predicted)
Density  2.052±0.06 g/cm3(Predicted)
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
pka -2.00±0.10(Predicted)
form  Crystalline Powder or Flakes
color  Off-white to yellow-beige
Water Solubility  insoluble
Sensitive  Light Sensitive
BRN  108889
CAS DataBase Reference 69045-79-0(CAS DataBase Reference)

Description and Uses

2-Chloro-5-iodopyridine may be used as a reagent in the multi-step synthesis of (±)-epibatidine.
It may be used in the synthesis of:

  • 2-Chloro-5-phenylpyridine via Suzuki coupling reaction with phenylboronic acid dimethyl ester.
  • Exo-5- and exo-6- (6′-chloro-3′-pyridyl)-2-azabicyclo[2.2.1]heptanes via Heck coupling reaction with N-protected 2-azabicyclo[2.2.1]hept-5-enes.
  • Substituted diaryliodonium salts.
  • 3-Exo-5′-(2′-Chloropyridinyl)-8-(ethoxycarbonyl)-8-azabicyclo[3.2.1]octane.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-20/22
Safety Statements  26-36-36/37/39-22
WGK Germany  3
Hazard Note  Irritant/Light Sensitive
HazardClass  IRRITANT
HS Code  29333990

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