Home Categories Chemical Reagents 3-Chloropropionyl chloride
A2333512

3-Chloropropionyl chloride , 96% , 625-36-5

CAS NO.:625-36-5

Empirical Formula: C3H4Cl2O

Molecular Weight: 126.97

MDL number: MFCD00000747

EINECS: 210-890-4

Pack Size Price Stock Quantity
25G RMB37.60 In Stock
100G RMB80.00 In Stock
500G RMB237.60 In Stock
2.5kg RMB907.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: -32 °C
Boiling point: 143-145 °C(lit.)
Density  1.33 g/mL at 25 °C(lit.)
vapor pressure  10.0 hPa
refractive index  n20/D 1.457(lit.)
RTECS  UC3934000
Flash point: 146 °F
storage temp.  Flammables area
solubility  Chloroform, Ethyl Acetate
form  liquid
color  red-brown
PH <7 (H2O)
explosive limit 8.8-20.2%(V)
Water Solubility  reacts
Sensitive  Moisture Sensitive
BRN  635814
Stability: Moisture Sensitive
InChIKey INUNLMUAPJVRME-UHFFFAOYSA-N

Description and Uses

3-Chloropropionyl chloride is an important bifunctional reagent. It is capable of acylation and possesses a 2-chloro-ethyl fragment (CH2CH2Cl), which can be subjected to nucleophilic substitution and serves as a masked vinyl group. It can be used as a starting material in many reactions to construct a variety of (hetero)cyclic compounds.

3-Chloropropionyl chloride is a reagent used in the synthesis of Beclamide (B119400), which is a chlorinated benzylpropanamide used as an anticonvulsant drug. It is used in the treatment of tonic-clonic seizyres and has sedative properties.

Safety

Symbol(GHS) 
GHS05,GHS06
Signal word  Danger
Hazard statements  H302-H314-H330
Precautionary statements  P260-P280-P301+P312-P303+P361+P353-P304+P340+P310-P305+P351+P338
Hazard Codes  T+
Risk Statements  14-22-26-34-35-10
Safety Statements  23-26-36/37/39-45-38-16-8
RIDADR  UN 3390 6.1/PG 1
WGK Germany  1
21
TSCA  Yes
HazardClass  6.1
PackingGroup  I
HS Code  29159080

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