3-Chloropropionyl chloride , 96% , 625-36-5
CAS NO.:625-36-5
Empirical Formula: C3H4Cl2O
Molecular Weight: 126.97
MDL number: MFCD00000747
EINECS: 210-890-4
Pack Size | Price | Stock | Quantity |
25G | RMB37.60 | In Stock |
|
100G | RMB80.00 | In Stock |
|
500G | RMB237.60 | In Stock |
|
2.5kg | RMB907.20 | In Stock |
|
others | Enquire |
PRODUCT Properties
Melting point: | -32 °C |
Boiling point: | 143-145 °C(lit.) |
Density | 1.33 g/mL at 25 °C(lit.) |
vapor pressure | 10.0 hPa |
refractive index | n |
RTECS | UC3934000 |
Flash point: | 146 °F |
storage temp. | Flammables area |
solubility | Chloroform, Ethyl Acetate |
form | liquid |
color | red-brown |
PH | <7 (H2O) |
explosive limit | 8.8-20.2%(V) |
Water Solubility | reacts |
Sensitive | Moisture Sensitive |
BRN | 635814 |
Stability: | Moisture Sensitive |
InChIKey | INUNLMUAPJVRME-UHFFFAOYSA-N |
Description and Uses
3-Chloropropionyl chloride is an important bifunctional reagent. It is capable of acylation and possesses a 2-chloro-ethyl fragment (CH2CH2Cl), which can be subjected to nucleophilic substitution and serves as a masked vinyl group. It can be used as a starting material in many reactions to construct a variety of (hetero)cyclic compounds.
3-Chloropropionyl chloride is a reagent used in the synthesis of Beclamide (B119400), which is a chlorinated benzylpropanamide used as an anticonvulsant drug. It is used in the treatment of tonic-clonic seizyres and has sedative properties.
Safety
Symbol(GHS) | GHS05,GHS06 |
Signal word | Danger |
Hazard statements | H302-H314-H330 |
Precautionary statements | P260-P280-P301+P312-P303+P361+P353-P304+P340+P310-P305+P351+P338 |
Hazard Codes | T+ |
Risk Statements | 14-22-26-34-35-10 |
Safety Statements | 23-26-36/37/39-45-38-16-8 |
RIDADR | UN 3390 6.1/PG 1 |
WGK Germany | 1 |
F | 21 |
TSCA | Yes |
HazardClass | 6.1 |
PackingGroup | I |
HS Code | 29159080 |