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A2316912

Cytisine , 98% , 485-35-8

Synonym(s):
Laburnin;Sophorine;Ulexine;nAChR Agonist, (-)-Cytisine, Nicotinic Acetylcholine Receptor Agonist, (-)-Cytisine, Baptitoxine, Sophorine;(?)-Cytisine

CAS NO.:485-35-8

Empirical Formula: C11H14N2O

Molecular Weight: 190.24

MDL number: MFCD00136048

EINECS: 207-616-0

Pack Size Price Stock Quantity
25MG RMB151.20 In Stock
100MG RMB439.20 In Stock
500MG RMB1351.20 In Stock
1g RMB2152.80 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 154-156 °C (lit.)
Boiling point: 218 °C/2 mmHg (lit.)
alpha  D17 -120°
Density  1.0815 (rough estimate)
refractive index  1.5700 (estimate)
storage temp.  Keep in dark place,Sealed in dry,2-8°C
solubility  439g/l
pka 6.11, 13.08(at 25℃)
form  powder
color  light yellow
optical activity [α]/D -108±3°, c = 1% in ethanol
Water Solubility  439g/L(16 ºC)
Merck  14,2789
InChIKey ANJTVLIZGCUXLD-DTWKUNHWSA-N
LogP 0.172 (est)
CAS DataBase Reference 485-35-8
NIST Chemistry Reference Cytisine(485-35-8)
EPA Substance Registry System Cytisine (485-35-8)

Description and Uses

It is an alkaloid that occurs naturally in several plant genera, such as Laburnum and Cytisus of the family Fabaceae. Pi-Zhen-Ye-Huang-Hua (Thermopsis lanceolata R.Br) contains large amount of cytisine, and it is distributed in the northeast, north, and northwest of China. This herb has been traditionally used for treating cough in China and was recorded in “Yue-Wang-Yao-Zhen,”“Jing-ZhuBen-Cao,”“Zhong-Hua-Ben-Cao,” and “Ning-Xia-Zhong-Cao-Yao-Shou-Ce.”

Toxic priniciple in seed of Laburnum anagyroides and other Leguminosae. A neuronal nicotinic acetylcholine agonist. Toxic priniciple in seed of Laburnum anagyroides and other Leguminosae. A neuronal nicotinic acetylcholine agonist.

Safety

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H301+H311+H331
Precautionary statements  P261-P264-P280-P301+P310-P302+P352+P312-P304+P340+P311
Hazard Codes  T
Risk Statements  25-36/37/38
Safety Statements  26-28-36/37-45
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  HA4025000
HazardClass  6.1(b)
PackingGroup  III
HS Code  29399990
Hazardous Substances Data 485-35-8(Hazardous Substances Data)
Toxicity LD50 in mice (mg/kg): 1.73 i.v.; 9.4 i.p.; 101 orally (Barlow, McLeod)

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