Cytisine , Analysis standard , 485-35-8
Synonym(s):
Laburnin;Sophorine;Ulexine;nAChR Agonist, (-)-Cytisine, Nicotinic Acetylcholine Receptor Agonist, (-)-Cytisine, Baptitoxine, Sophorine;(?)-Cytisine
CAS NO.：485-35-8
Empirical Formula: C11H14N2O
Molecular Weight: 190.24
MDL number: MFCD00136048
EINECS: 207-616-0
| Pack Size | Price | Stock | Quantity |
| 20MG | RMB238.40 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 154-156 °C (lit.) |
| Boiling point: | 218 °C/2 mmHg (lit.) |
| alpha | D17 -120° |
| Density | 1.0815 (rough estimate) |
| refractive index | 1.5700 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,2-8°C |
| solubility | 439g/l |
| pka | 6.11, 13.08(at 25℃) |
| form | powder |
| color | light yellow |
| optical activity | [α]/D -108±3°, c = 1% in ethanol |
| Water Solubility | 439g/L(16 ºC) |
| Merck | 14,2789 |
| InChIKey | ANJTVLIZGCUXLD-DTWKUNHWSA-N |
| LogP | 0.172 (est) |
| CAS DataBase Reference | 485-35-8 |
| NIST Chemistry Reference | Cytisine(485-35-8) |
| EPA Substance Registry System | Cytisine (485-35-8) |
Description and Uses
It is an alkaloid that occurs naturally in several plant genera, such as Laburnum and Cytisus of the family Fabaceae. Pi-Zhen-Ye-Huang-Hua (Thermopsis lanceolata R.Br) contains large amount of cytisine, and it is distributed in the northeast, north, and northwest of China. This herb has been traditionally used for treating cough in China and was recorded in “Yue-Wang-Yao-Zhen,”“Jing-ZhuBen-Cao,”“Zhong-Hua-Ben-Cao,” and “Ning-Xia-Zhong-Cao-Yao-Shou-Ce.”
Toxic priniciple in seed of Laburnum anagyroides and other Leguminosae. A neuronal nicotinic acetylcholine agonist. Toxic priniciple in seed of Laburnum anagyroides and other Leguminosae. A neuronal nicotinic acetylcholine agonist.
Safety
| Symbol(GHS) |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301+H311+H331 |
| Precautionary statements | P261-P264-P280-P301+P310-P302+P352+P312-P304+P340+P311 |
| Hazard Codes | T |
| Risk Statements | 25-36/37/38 |
| Safety Statements | 26-28-36/37-45 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | HA4025000 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| HS Code | 29399990 |
| Hazardous Substances Data | 485-35-8(Hazardous Substances Data) |
| Toxicity | LD50 in mice (mg/kg): 1.73 i.v.; 9.4 i.p.; 101 orally (Barlow, McLeod) |
