Home Categories Chemical Reagents 15-Crown-5
A2301412

15-Crown-5 , 97% , 33100-27-5

Synonym(s):
1,4,7,10,13-Pentaoxacyclopentadecane;15C5

CAS NO.:33100-27-5

Empirical Formula: C10H20O5

Molecular Weight: 220.26

MDL number: MFCD00005110

EINECS: 251-379-6

Pack Size Price Stock Quantity
1G RMB23.20 In Stock
5G RMB57.60 In Stock
25G RMB192.80 In Stock
100G RMB655.20 In Stock
500g RMB2559.20 In Stock
others     Enquire
Update time: 2022-07-08

PRODUCT Properties

Melting point: -20°C(lit.)
Boiling point: 93-96 °C/0.05 mmHg (lit.)
Density  1.113 g/mL at 20 °C (lit.)
vapor pressure  0.5-0.82Pa at 20-25℃
refractive index  n20/D 1.465(lit.)
Flash point: >230 °F
storage temp.  room temp
solubility  Miscible with organic solvents.
form  Liquid
color  Clear colorless to light yellow
Specific Gravity 1.109
Water Solubility  MISCIBLE
Sensitive  Hygroscopic
BRN  1618144
Stability: Stable. Incompatible with oxidizing agents, strong acids. Avoid exposure to water or moist air.
LogP -0.9 at 20℃ and pH7.7
Surface tension 68.5mN/m at 1g/L and 20℃
CAS DataBase Reference 33100-27-5(CAS DataBase Reference)
NIST Chemistry Reference 15-Crown-5(33100-27-5)
EPA Substance Registry System 1,4,7,10,13-Pentaoxacyclopentadecane (33100-27-5)

Description and Uses

15-Crown-5 is used as an efficient phase transfer catalyst and as a complexing agent. It is used to isolate oxonium ion (H7O3)+ salts especially from a solution of tetrchloroauric acid. It catalyzes the O-alkylation of the sodium salts of carboxylic acids in the penicillin and cephalosporin series, thereby facilitating esterification reaction without usage of acid. It is also used to facilitate the Williamson synthesis of ethers with hindered alcohols and sodium hydride. It is used with lithium aluminum hydride, for performing reduction reactions in hydrocarbon solvents. Further, it is involved in the Horner-Wadsworth-Emmons reaction to prepare stilbenes from aldehydes.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P301+P312+P330
Hazard Codes  Xn,Xi
Risk Statements  22-36/38-36-20/22-36/37/38-20/21/22
Safety Statements  26-39-36
RIDADR  2810
WGK Germany  3
RTECS  SB0200000
10-21
Hazard Note  Irritant
TSCA  Yes
HazardClass  6.1(b)
PackingGroup  III
HS Code  29329995
Toxicity LD50 orl-rat: 1410 mg/kg DCTODJ 1,339,78

RELATED PRODUCTS