A2296312
6-Carboxyfluorescein , 95% , 3301-79-9
Synonym(s):
6-Carboxyfluorescein;6-FAM;FLUOS
CAS NO.:3301-79-9
Empirical Formula: C21H12O7
Molecular Weight: 376.32
MDL number: MFCD00036873
EINECS: 636-503-2
Pack Size | Price | Stock | Quantity |
25MG | RMB39.20 | In Stock |
|
100MG | RMB110.40 | In Stock |
|
500MG | RMB399.20 | In Stock |
|
1g | RMB604.80 | In Stock |
|
5g | RMB2103.20 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | >300 °C(lit.) |
Boiling point: | 736.4±60.0 °C(Predicted) |
Density | 1.73±0.1 g/cm3(Predicted) |
storage temp. | Sealed in dry,2-8°C |
solubility | DMSO: soluble |
pka | 3.3, 4.6, 6.4, 7.0(at 25℃) |
form | Solid |
color | Yellow to orange |
PH Range | Weak green ' uorescence (6.0) to strong green ' uourescence (7.2) |
λmax | 492nm |
BRN | 54341 |
Major Application | Diagnosis of hematologic cancer, nongastric diseases, detection of genetically modified wheat, chromosomes, gene expression, nucleic acid, hepatitis A virus, avian influenza virus subtype H5 and H5N1, SARS virus, herpex simplex virus |
Biological Applications | Diagnosing bladder cancer; evaluating corneal endothelial barrier function; as a substrate for measuring protein kinase activity, methyltransferase activity, phospholipase activity, rhodanese activity,sulfotransferase activity;use in ophthalmology |
Description and Uses
6-Carboxyfluorescein (6-FAM) is derivative of fluorescein giving stable derivative upon conjugation with biopolymers.It has been used to check the plasma membrane integrity in sperm cells. The single isomer, 6-FAM, contains a carboxylic acid that can be used to react with primary amines via carbodiimide activation of the carboxylic acid. Commercially available FAM is a mixture of two isomers, 5-FAM and 6-FAM, and the correct name is 5(6)-carboxyfluorescein.