A2296312
6-Carboxyfluorescein , 95% , 3301-79-9
Synonym(s):
6-Carboxyfluorescein;6-FAM;FLUOS
CAS NO.：3301-79-9
Empirical Formula: C21H12O7
Molecular Weight: 376.32
MDL number: MFCD00036873
EINECS: 636-503-2
| Pack Size | Price | Stock | Quantity |
| 25MG | RMB39.20 | In Stock |
|
| 100MG | RMB110.40 | In Stock |
|
| 500MG | RMB399.20 | In Stock |
|
| 1g | RMB604.80 | In Stock |
|
| 5g | RMB2103.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | >300 °C(lit.) |
| Boiling point: | 736.4±60.0 °C(Predicted) |
| Density | 1.73±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | DMSO: soluble |
| form | Solid |
| pka | 3.3, 4.6, 6.4, 7.0(at 25℃) |
| color | Yellow to orange |
| PH Range | Weak green ' uorescence (6.0) to strong green ' uourescence (7.2) |
| λmax | 492nm |
| BRN | 54341 |
| Major Application | Diagnosis of hematologic cancer, nongastric diseases, detection of genetically modified wheat, chromosomes, gene expression, nucleic acid, hepatitis A virus, avian influenza virus subtype H5 and H5N1, SARS virus, herpex simplex virus |
| Biological Applications | Diagnosing bladder cancer; evaluating corneal endothelial barrier function; as a substrate for measuring protein kinase activity, methyltransferase activity, phospholipase activity, rhodanese activity,sulfotransferase activity;use in ophthalmology |
| CAS DataBase Reference | 3301-79-9(CAS DataBase Reference) |
| EPA Substance Registry System | Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-carboxylic acid, 3',6'-dihydroxy-3-oxo- (3301-79-9) |
Description and Uses
6-Carboxyfluorescein (6-FAM) is derivative of fluorescein giving stable derivative upon conjugation with biopolymers.It has been used to check the plasma membrane integrity in sperm cells. The single isomer, 6-FAM, contains a carboxylic acid that can be used to react with primary amines via carbodiimide activation of the carboxylic acid. Commercially available FAM is a mixture of two isomers, 5-FAM and 6-FAM, and the correct name is 5(6)-carboxyfluorescein.
