A2277512
1-Chloroisoquinoline , 98% , 19493-44-8
CAS NO.：19493-44-8
Empirical Formula: C9H6ClN
Molecular Weight: 163.6
MDL number: MFCD00024134
EINECS: 628-561-2
| Pack Size | Price | Stock | Quantity |
| 1G | RMB40.00 | In Stock |
|
| 5G | RMB158.40 | In Stock |
|
| 25G | RMB639.20 | In Stock |
|
| 100g | RMB1987.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 31-36 °C (lit.) |
| Boiling point: | 274-275 °C/768 mmHg (lit.) |
| Density | 1.2108 (rough estimate) |
| refractive index | 1.6342 (estimate) |
| Flash point: | >230 °F |
| storage temp. | Inert atmosphere,2-8°C |
| pka | 2.03±0.30(Predicted) |
| form | Low Melting Solid, Crystals and/or Chunks |
| color | White to yellow |
| Water Solubility | Insoluble in water. |
| BRN | 2996 |
| InChIKey | MSQCQINLJMEVNJ-UHFFFAOYSA-N |
| CAS DataBase Reference | 19493-44-8(CAS DataBase Reference) |
Description and Uses
The product has been used in a Mn-catalyzed cross-coupling with aryl- and alkylmagnesium halides. It has also been used in a Pd-catalyzed cross-coupling with heteroaryl boronic acids and esters. Furthermore, it has been used in a homocoupling reaction to yield bis-isoquinoline, each enantiomer of which might be very useful as a chiral ligand for asymmetric synthesis. 1-Chloroisoquinone is used in the preparation of new aminoisoquinolinylurea derivatives which show antiproliferative activity against melanoma cell lines. It can also be applied to the control of storage age and stability of unstable boronic acids.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| HS Code | 29334900 |
