Home Categories Pharmaceutical intermediates 2-Chloropyridine-3-boronic acid
A2269512

2-Chloropyridine-3-boronic acid , 97% , 381248-04-0

Synonym(s):
(2-Chloro-3-pyridyl)boronic acid;(2-Chloropyridin-3-yl)boronic acid;Dihydroxy(2-chloro-3-pyridyl)borane

CAS NO.:381248-04-0

Empirical Formula: C5H5BClNO2

Molecular Weight: 157.36

MDL number: MFCD03094997

EINECS: 624-435-6

Pack Size Price Stock Quantity
250MG RMB23.20 In Stock
1G RMB42.40 In Stock
5G RMB118.40 In Stock
25G RMB492.80 In Stock
100G RMB1295.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 121-134 °C
Boiling point: 349.3±52.0 °C(Predicted)
Density  1.41±0.1 g/cm3(Predicted)
storage temp.  2-8°C
solubility  soluble in Methanol
pka 6.59±0.58(Predicted)
form  Crystalline Powder
color  White
BRN  9119913
InChIKey VRDAOVQZVXYRNH-UHFFFAOYSA-N
CAS DataBase Reference 381248-04-0(CAS DataBase Reference)

Description and Uses

Reactant for:

  • Synthesis of Et canthinone-3-carboxylates from Et 4-bromo-6-methoxy-1,5-naphthyridine-3-carboxylate via a Pd-catalyzed Suzuki-Miyaura coupling and a Cu-catalyzed amidation reaction
  • Preparation of arylmethylpyrrolidinylmethanols and amine derivatives via reaction with MIDA followed by Suzuki reaction with halides or amination with amines
  • Preparation of arylazabicyclooctane derivatives as potential arginine vasopressin receptor antagonists
  • Regioselective preparation of halo-oligopyridines and oligopyridines by the Suzuki-Miyaura cross-coupling reaction

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38-20/21/22
Safety Statements  26-36-36/37/39-24/25-22
RIDADR  2811
WGK Germany  3
Hazard Note  Irritant/Keep Cold
HazardClass  IRRITANT
HS Code  29333990

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