A1643250
ML141 , ≥98% , 71203-35-5
Synonym(s):
4-[4,5-Dihydro-5-(4-methoxyphenyl)-3-phenyl-1H-pyrazol-1-yl]-benzenesulfonamide;z;Cdc42/Rac1 GTPase Inhibitor, ML141 - Calbiochem
Pack Size | Price | Stock | Quantity |
5mg | RMB345.60 | In Stock |
|
10mg | RMB639.20 | In Stock |
|
25mg | RMB1519.20 | In Stock |
|
50mg | RMB2959.20 | In Stock |
|
100mg | RMB5183.20 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 216 °C(Solv: ethanol (64-17-5)) |
Boiling point: | 622.9±65.0 °C(Predicted) |
Density | 1.31±0.1 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | DMSO: soluble5mg/mL (warmed, clear solution) |
form | Yellow-white solid |
pka | 10.39±0.10(Predicted) |
color | white to beige |
Description and Uses
ML 141 has been used:
- to inhibit CDC42 GTPase in human immortalized gingival epithelial (HIGE) cells
- as inhibitors of Rho kinase to study the role of small Rho GTPases on localization of peripheral nuclei
- as actin regulator inhibitor, to determine which actin regulators and nucleators are involved in the assembly of F-actin cages around damaged mitochondria
- as a selective, non-competitive inhibitor of Cdc42 to treat CCD-1070Sk cells
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H302-H315-H320-H335 |
Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
WGK Germany | 3 |