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A1643250

ML141 , ≥98% , 71203-35-5

Synonym(s):
4-[4,5-Dihydro-5-(4-methoxyphenyl)-3-phenyl-1H-pyrazol-1-yl]-benzenesulfonamide;z;Cdc42/Rac1 GTPase Inhibitor, ML141 - Calbiochem

CAS NO.:71203-35-5

Empirical Formula: C22H21N3O3S

Molecular Weight: 407.49

MDL number: MFCD05987165

Pack Size Price Stock Quantity
5mg RMB345.60 In Stock
10mg RMB639.20 In Stock
25mg RMB1519.20 In Stock
50mg RMB2959.20 In Stock
100mg RMB5183.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 216 °C(Solv: ethanol (64-17-5))
Boiling point: 622.9±65.0 °C(Predicted)
Density  1.31±0.1 g/cm3(Predicted)
storage temp.  2-8°C
solubility  DMSO: soluble5mg/mL (warmed, clear solution)
form  Yellow-white solid
pka 10.39±0.10(Predicted)
color  white to beige

Description and Uses

ML 141 has been used:

  • to inhibit CDC42 GTPase in human immortalized gingival epithelial (HIGE) cells
  • as inhibitors of Rho kinase to study the role of small Rho GTPases on localization of peripheral nuclei
  • as actin regulator inhibitor, to determine which actin regulators and nucleators are involved in the assembly of F-actin cages around damaged mitochondria
  • as a selective, non-competitive inhibitor of Cdc42 to treat CCD-1070Sk cells

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H320-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
WGK Germany  3

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