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A1642050

Menaquinone-7 , ≥97% , 2124-57-4

Synonym(s):
Menaquinone-7-(5,6,7,8-d4,2-methyl-d3)

CAS NO.:2124-57-4

Empirical Formula: C46H64O2

Molecular Weight: 649

MDL number: MFCD06200757

Pack Size Price Stock Quantity
5mg RMB319.20 In Stock
25mg RMB1119.20 In Stock
100mg RMB3759.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 54 °C
Boiling point: bp0.0002 200° (some dec)
Density  0.961
storage temp.  -20°C
solubility  Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form  Solid
color  Pale Yellow to Yellow
Stability: Light and Temperature Sensitive
InChIKey RAKQPZMEYJZGPI-LJWNYQGCSA-N
SMILES C1(=O)C2=C(C=CC=C2)C(=O)C(C)=C1C/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(/C)\C
LogP 14.451 (est)

Description and Uses

Menaquinone 7 (MK-7) is a vitamin K2 analog that has been found in a variety of fermented foods. It increases osteocalcin, osteoprotegerin, and RANKL mRNA expression in osteoblastic MC3T3E cells. MK-7 (1 μM) increases alkaline phosphatase activity and calcium content in femoral-metaphyseal tissues isolated from normal and skeletal-unloaded rats. In vivo, MK-7 (100 μg/g diet) inhibits aortic and myocardial calcification and decreases aortic alkaline phosphatase tissue concentrations in a rat model of extraosseous calcification. It also increases trabecular number, bone mineral density, and bone mineral content in a rat model of ovariectomy-induced bone loss.

Vitamin (prothrombogenic)

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319
Precautionary statements  P261-P305+P351+P338
HS Code  2936299055
Hazardous Substances Data 2124-57-4(Hazardous Substances Data)

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