Menaquinone-7 , ≥97% , 2124-57-4
Synonym(s):
Menaquinone-7-(5,6,7,8-d4,2-methyl-d3)
Pack Size | Price | Stock | Quantity |
5mg | RMB319.20 | In Stock |
|
25mg | RMB1119.20 | In Stock |
|
100mg | RMB3759.20 | In Stock |
|
others | Enquire |
PRODUCT Properties
Melting point: | 54 °C |
Boiling point: | bp0.0002 200° (some dec) |
Density | 0.961 |
storage temp. | -20°C |
solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
form | Solid |
color | Pale Yellow to Yellow |
Stability: | Light and Temperature Sensitive |
InChIKey | RAKQPZMEYJZGPI-LJWNYQGCSA-N |
SMILES | C1(=O)C2=C(C=CC=C2)C(=O)C(C)=C1C/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(/C)\C |
LogP | 14.451 (est) |
Description and Uses
Menaquinone 7 (MK-7) is a vitamin K2 analog that has been found in a variety of fermented foods. It increases osteocalcin, osteoprotegerin, and RANKL mRNA expression in osteoblastic MC3T3E cells. MK-7 (1 μM) increases alkaline phosphatase activity and calcium content in femoral-metaphyseal tissues isolated from normal and skeletal-unloaded rats. In vivo, MK-7 (100 μg/g diet) inhibits aortic and myocardial calcification and decreases aortic alkaline phosphatase tissue concentrations in a rat model of extraosseous calcification. It also increases trabecular number, bone mineral density, and bone mineral content in a rat model of ovariectomy-induced bone loss.
Vitamin (prothrombogenic)
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H302-H315-H319 |
Precautionary statements | P261-P305+P351+P338 |
HS Code | 2936299055 |