PRODUCT Properties
Melting point: | 177-181℃ |
Boiling point: | 453.11°C (rough estimate) |
Density | 1.2016 (rough estimate) |
refractive index | 1.4500 (estimate) |
storage temp. | Sealed in dry,Room Temperature |
solubility | DMSO (Slightly), Methanol (Slightly) |
pka | 14.17±0.70(Predicted) |
form | Solid |
color | White |
Water Solubility | 20mg/L(21 ºC) |
Merck | 14,1045 |
CAS DataBase Reference | 5003-48-5(CAS DataBase Reference) |
Description and Uses
Benorylate is the acetaminophen ester of acetylsalicylic acid, designed to provide a less irritating form of aspirin. Gastrointestinal blood loss in patients taking benorylate is less than that during therapy with soluble aspirin. Benorylate has been found to be as effective as aspirin for the treatment of chronic rheumatic disorders.
Benorilate is a codrug of Acetylsalicylic Acid (A187780) and Acetaminophen (A161220) and is used as an anti-inflammatory and antipyretic medication.
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H302-H315-H319-H332-H335 |
Precautionary statements | P261-P280-P305+P351+P338 |
RTECS | VO0720000 |
HS Code | 2924.29.7790 |
Toxicity | LD50 in mice, rats (mg/ml): 2000, ~10000 orally; 1255, 1830 i.p. (Robertson) |