Home Categories Pharmaceutical intermediates 4-Bromomethyl-6,7-dimethoxycoumarin [for HPLC Labeling]
A1501612

4-Bromomethyl-6,7-dimethoxycoumarin [for HPLC Labeling] , >98.0%(HPLC) , 88404-25-5

CAS NO.:88404-25-5

Empirical Formula: C12H11BrO4

Molecular Weight: 299.12

MDL number: MFCD00011570

Pack Size Price Stock Quantity
25mg RMB79.20 In Stock
100MG RMB239.20 In Stock
500mg RMB799.20 In Stock
1G RMB1439.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 212-216 °C(lit.)
Density  1.6176 (rough estimate)
refractive index  1.4490 (estimate)
storage temp.  Inert atmosphere,2-8°C
solubility  Soluble in acetonitrile, dichloromethane, N,N-dimethylformamide, methanol
form  Powder
color  Yellow crystals or powder
Water Solubility  Insoluble in water.
λmax 348 nm (MeOH)
BRN  4750487
Major Application Electrostatic imaging process; resists; printed circuit boards; semiconductor devices
Biological Applications Analyzing bile acid; anticancer agents; identifying bacteria; identifying/measuring lauric acid metabolites; measuring cyclosporine; studying/monitoring early stages of protein folding;treating gastrointestinal diseases; derivatization reagent for carboxylic acids; as a substrate for measuring lauric acid hydroxylase activity

Description and Uses

4-Bromomethyl-6,7-dimethoxycoumarin was used as fluorescent labeling reagent for the reversed-phase HPLC separation and detection of carboxylic acids. It was also used as derivatization reagent:

  • for quantitation of clofibric, bezafibric and fenofibric acids in liver by liquid chromatography
  • in determination of the concentration of tripeptide glutathione by matrix-assisted laser desorption ionization time-of-flight mass spectrometry
  • for determination of carboxylic acids in chromatographic detection

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P301+P312-P302+P352-P305+P351+P338
Hazard Codes  Xn,C
Risk Statements  22-36/37/38
Safety Statements  26
RIDADR  1759
WGK Germany  3
21
Hazard Note  Corrosive
HazardClass  8
PackingGroup  III
HS Code  29322090

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