4-Bromomethyl-7-methoxycoumarin , ≥97% , 35231-44-8

Synonym(s):
BMC;Br-Mmc

Update time: 2022-07-08

Melting point:	213-215 °C (lit.)
Boiling point:	385.3±42.0 °C(Predicted)
Density	1.552±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,2-8°C
solubility	chloroform: soluble20mg/mL, clear, colorless to faintly yellow
form	Powder and/or Chunks
color	Off-white to light yellow or beige
Water Solubility	insoluble
λmax	330 nm (MeOH)
BRN	187211
Stability:	Stable, but moisture and light-sensitive. Combustible. Incompatible with strong oxidizing agents.
Major Application	Detection of nitrated explosives; measuring ultraviolet ray power; photoacid generators; polyurethane foams; photoresists silica nanoparticles
Biological Applications	Analyzing/detecting carboxylic acids;analyzing/labeling fatty acids; detecting nitric oxide; detecting/separating bile acids; labeling pyrimidine nucleobases; anticancer agents; biomedical trace analysis; herbicides; as a substrate for measuring histone acetyltransferases (HATs) activity, peptidases activity, sirtuin activity
LogP	2.730 (est)
CAS DataBase Reference	35231-44-8(CAS DataBase Reference)

4-Bromomethyl-7-methoxycoumarin has been used:

as derivatization reagent in determination of 5-fluorouracil (5-FU) in human plasma by HPLC-tandem mass spectrometry
as derivatization reagent in fluorescence detection of sodium monofluoroacetate (MFA-Na) in biological samples by HPLC
in the synthesis of new caged derivatives of hydrolysis-resistant 8-bromoadenosine cyclic 3′,5′-monophosphate (8-Br-cAMP) and 8-bromoguanosine cyclic 3′,5′-monophosphate (8-Br-cGMP)
in TLC and HPLC separation and fluorometric analysis of a wide range of naturally occurring acids, including bile and thromboxane B₂