A1495712
3'-Bromo-4'-methylacetophenone , >98.0%(GC) , 40180-80-1
Pack Size | Price | Stock | Quantity |
200MG | RMB48.00 | In Stock |
|
1G | RMB143.20 | In Stock |
|
5G | RMB293.60 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 42-46 °C(lit.) |
Boiling point: | 118°C/3mmHg(lit.) |
Density | 1.388±0.06 g/cm3(Predicted) |
storage temp. | Inert atmosphere,Room Temperature |
solubility | Chloroform (Slightly), Methanol (Slightly) |
form | Solid |
color | Off-White to Pale Yellow |
Description and Uses
3''-Bromo-4''-methylacetophenone is used as a starting material in the synthesis of mansonone E which is used to make mansonone E dervivatives. These derivatives are potent inhibitors of topoisomerase II (Topo II) and topoisomerase I (Topo I) and are also potent antitumor agents. 3''-Bromo-4''-methylacetophenone is also used as a reagent in the synthesis of BAF312, Siponimod which has been tested in the treatment of patients suffering from relapsing-remitting multiple sclerosis.
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
WGK Germany | 3 |
HS Code | 2914390090 |