A1406412
Avagacestat (BMS-708163) , ≥99% , 1146699-66-2
Synonym(s):
(2R)-2-[N-[(4-Chlorophenyl)sulfonyl]-N-[[2-fluoro-4-(1,2,4-oxadiazol-3-yl)phenyl]methyl]amino]-5,5,5-trifluoropentanamide;(R)-2-(4-Chloro-N-(2-fluoro-4-(1,2,4-oxadiazol-3-yl)benzyl)phenylsulfonamido)-5,5,5-trifluoropentanamide;BMS-708163
CAS NO.：1146699-66-2
Empirical Formula: C20H17ClF4N4O4S
Molecular Weight: 520.89
MDL number: MFCD13195458
| Pack Size | Price | Stock | Quantity |
| 1MG | RMB386.40 | In Stock |
|
| 5MG | RMB799.20 | In Stock |
|
| 10MG | RMB1359.20 | In Stock |
|
| 50MG | RMB5036.80 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Density | 1.488 |
| storage temp. | Store at -20°C |
| solubility | insoluble in H2O; ≥177.6 mg/mL in DMSO; ≥47.6 mg/mL in EtOH with ultrasonic |
| form | Powder |
| color | White to off-white |
Description and Uses
Avagacestat acts as a γ-secretase inhibitor allowing for treatment of ALzheimer’s disease. On addition it has seen uses targeting embryonic signaling pathways, which control stem cell and cellular development process in cancer therapy.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501 |
