Home Categories Organic Chemistry Malonate
A1384650

Malonate , 99% , 141-82-2

Synonym(s):
13C Labeled malonic acid;Propanedioic acid;Propanedioic acid-13C3

CAS NO.:141-82-2

Empirical Formula: C3H4O4

Molecular Weight: 104.06

MDL number: MFCD00002707

EINECS: 205-503-0

Pack Size Price Stock Quantity
25g RMB39.20 In Stock
100g RMB60.80 In Stock
500g RMB207.20 In Stock
2.5kg RMB716.00 In Stock
others     Enquire
Update time: 2022-07-08

PRODUCT Properties

Melting point: 132-135 °C (dec.) (lit.)
Boiling point: 140℃(decomposition)
Density  1.619 g/cm3 at 25 °C
vapor pressure  0-0.2Pa at 25℃
refractive index  1.4780
Flash point: 157°C
storage temp.  Sealed in dry,Room Temperature
solubility  1 M NaOH: soluble100mg/mL, clear to slightly hazy, colorless to faintly yellow
form  Liquid
pka 2.83(at 25℃)
color  White
PH 3.17(1 mM solution);2.5(10 mM solution);1.94(100 mM solution)
Water Solubility  1400 g/L (20 ºC)
Merck  14,5710
BRN  1751370
Stability: Stable. Incompatible with oxidizing agents, reducing agents, bases.
InChIKey OFOBLEOULBTSOW-UHFFFAOYSA-N
LogP -0.81

Description and Uses

Malonic acid (MA), also known as propanedioic acid, is a dicarboxylic acid with structure CH2(COOH)2. It have three kinds of crystal forms, of which two are triclinic, and one is monoclinic. That crystallized from ethanol is white triclinic crystals.It decomposes to acetic acid and carbon dioxide at 140℃. It does not decompose at 1.067×103~1.333×103Pa vacuum, but directly sublimates. The ionised form of malonic acid, as well as its esters and salts, are known as malonates. For example, diethyl malonate is malonic acid's ethyl ester. The name originates from Latin malum, meaning apple.

Malonic acid is used as an intermediate in the manufacture of barbiturates and other pharmaceuticals. It is a component used as a stabilizer in many high-end cosmetic and pharmaceutical products. Malonic acid is also used as building block in chemical synthesis, specifically to introduce the molecular group -CH2-COOH. It is used for the introduction of an acetic acid moiety under mild conditions by Knoevenagel condensation and subsequent decarboxylation.

Safety

Symbol(GHS) 
GHS05
Signal word  Danger
Hazard statements  H318
Precautionary statements  P280-P305+P351+P338
Hazard Codes  Xn,Xi
Risk Statements  20/22-41-36/37/38-22
Safety Statements  26-36/39-37/39-36
RIDADR  3261
WGK Germany  1
RTECS  OO0175000
TSCA  Yes
PackingGroup  III
HS Code  29171910
Toxicity mouse,LD50,intraperitoneal,300mg/kg (300mg/kg),National Technical Information Service. Vol. AD277-689,

RELATED PRODUCTS