2-Bromo-3-fluoropyridine , 98% , 40273-45-8

CAS NO.：40273-45-8

Empirical Formula: C5H3BrFN

Molecular Weight: 175.99

MDL number: MFCD04114128

EINECS: 675-562-9

PRODUCT Properties

• Boiling point: 62°C
• Density: 1.74
• refractive index: 1.5450
• storage temp.: Keep in dark place,Sealed in dry,Room Temperature
• form: clear liquid
• pka: -1.63±0.10(Predicted)
• color: Colorless to Light yellow to Light orange

Description and Uses

2-Bromo-3-fluoropyridine is a chemical intermediate that belongs to the group of heterocyclic compounds. It is synthesized by the reaction of sodium methanethiolate and formaldehyde with magnesium. The product yield is not very high, but 2-bromo-3-fluoropyridine can be used for the synthesis of other heterocyclic compounds. The compound was first isolated in 1887 by J. Grignard from a reaction between bromine and formaldehyde. It has been shown to have formylation, nucleophilic substitution, and condensation reactions as its transition states. 2-Bromo-3-fluoropyridine can be prepared from the Grignard reagent, methanethiolate, and chlorine or magnesium chloride in an ether solution at room temperature. This compound has also been used as a reagent for the preparation of difluoromethoxybenz.

Safety

• Symbol(GHS): GHS02,GHS07,GHS06
• Signal word: Warning
• Hazard statements: H227-H301-H311-H332-H335-H226-H315-H319
• Precautionary statements: P210-P233-P240-P241+P242+P243-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P403+P235-P501-P280h-P305+P351+P338-P309-P310
• Hazard Codes: T,Xi,Xn
• Risk Statements: 22-37/38-41
• Safety Statements: 26-39
• RIDADR: 1993
• Hazard Note: Toxic
• HazardClass: IRRITANT
• HazardClass: 6.1
• PackingGroup: Ⅲ
• HS Code: 29333990