Home Categories Pharmaceutical intermediates 2-Bromo-3-fluoropyridine
A1325712

2-Bromo-3-fluoropyridine , 98% , 40273-45-8

CAS NO.:40273-45-8

Empirical Formula: C5H3BrFN

Molecular Weight: 175.99

MDL number: MFCD04114128

EINECS: 675-562-9

Pack Size Price Stock Quantity
1G RMB29.60 In Stock
5G RMB67.20 In Stock
25G RMB216.80 In Stock
100G RMB651.20 In Stock
others     Enquire
Update time: 2022-07-08

PRODUCT Properties

Boiling point: 62°C
Density  1.74
refractive index  1.5450
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
form  clear liquid
pka -1.63±0.10(Predicted)
color  Colorless to Light yellow to Light orange
CAS DataBase Reference 40273-45-8(CAS DataBase Reference)

Description and Uses

2-Bromo-3-fluoropyridine is a chemical intermediate that belongs to the group of heterocyclic compounds. It is synthesized by the reaction of sodium methanethiolate and formaldehyde with magnesium. The product yield is not very high, but 2-bromo-3-fluoropyridine can be used for the synthesis of other heterocyclic compounds. The compound was first isolated in 1887 by J. Grignard from a reaction between bromine and formaldehyde. It has been shown to have formylation, nucleophilic substitution, and condensation reactions as its transition states. 2-Bromo-3-fluoropyridine can be prepared from the Grignard reagent, methanethiolate, and chlorine or magnesium chloride in an ether solution at room temperature. This compound has also been used as a reagent for the preparation of difluoromethoxybenz.

Safety

Symbol(GHS) 
GHS02,GHS07,GHS06
Signal word  Warning
Hazard statements  H227-H301-H311-H332-H335-H226-H315-H319
Precautionary statements  P210-P233-P240-P241+P242+P243-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P403+P235-P501-P280h-P305+P351+P338-P309-P310
Hazard Codes  T,Xi,Xn
Risk Statements  22-37/38-41
Safety Statements  26-39
RIDADR  1993
Hazard Note  Toxic
HazardClass  IRRITANT
HazardClass  6.1
PackingGroup 
HS Code  29333990

RELATED PRODUCTS