Ethyl Bromodifluoroacetate , 97% , 667-27-6

CAS NO.：667-27-6

Empirical Formula: C4H5BrF2O2

Molecular Weight: 202.98

MDL number: MFCD00042069

EINECS: 211-567-0

PRODUCT Properties

• Boiling point: 112 °C/700 mmHg (lit.)
• Density: 1.583 g/mL at 25 °C (lit.)
• refractive index: n20/D 1.387(lit.)
• Flash point: 70 °F
• storage temp.: Keep in dark place,Inert atmosphere,Room temperature
• solubility: Soluble in most organic solvents.
• form: Liquid
• Specific Gravity: 1.583
• color: Clear colorless to slightly yellow
• BRN: 1906095
• InChI: InChI=1S/C4H5BrF2O2/c1-2-9-3(8)4(5,6)7/h2H2,1H3
• InChIKey: IRSJDVYTJUCXRV-UHFFFAOYSA-N
• SMILES: C(OCC)(=O)C(Br)(F)F
• CAS DataBase Reference: 667-27-6(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl bromodifluoroacetate(667-27-6)

Description and Uses

Ethyl bromodifluoroacetate, a clear to yellow liquid, is an ester of bromodifluoroacetic acid and ethyl alcohol. It is an ester that can be used to introduce the CF2 group when synthesizing chemical compounds. Ethyl bromdifluoroacetate is considered to be a good compound in the generation of compounds and for testing with other organic compounds like lactones, imines, and other amino acids.

Efficient difluoroalkylation of aryl boronic acids via palladium catalysis. Novel, moisture-stable bromodifluoromethylated phosphonate, ester, and amide. Efficient coupling with aryl boronic acids via Pd catalysis. A Cu-catalyzed regioselective bromodifluoroacetylation of alkenes, using ethyl bromodifluoroacetate (BrCF2CO2Et) as a difluoroacetylating reagent.

Safety

• Symbol(GHS): GHS02,GHS05
• Signal word: Danger
• Hazard statements: H225-H314
• Precautionary statements: P210-P233-P240-P280-P303+P361+P353-P305+P351+P338
• Hazard Codes: C,F,Xi
• Risk Statements: 10-34-36
• Safety Statements: 26-36/37/39-45-16-27
• RIDADR: UN 2924 3/PG 2
• WGK Germany: 3
• Hazard Note: Irritant/Flammable
• TSCA: No
• HazardClass: 3
• PackingGroup: II
• HS Code: 29159000