Echinacoside , Analysis of standard products, ≥98% , 82854-37-3
| Pack Size | Price | Stock | Quantity |
| 10MG | RMB559.20 | In Stock |
|
| 20MG | RMB744.80 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Boiling point: | 1062.7±65.0 °C(Predicted) |
| Density | 1.66±0.1 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | DMSO:60.0(Max Conc. mg/mL);76.26(Max Conc. mM) DMSO:PBS (pH 7.2) (1:9):0.1(Max Conc. mg/mL);0.13(Max Conc. mM) DMF:30.0(Max Conc. mg/mL);38.13(Max Conc. mM) Ethanol:52.5(Max Conc. mg/mL);66.73(Max Conc. mM) Water:24.36(Max Conc. mg/mL);30.96(Max Conc. mM) |
| form | powder |
| pka | 8.43±0.20(Predicted) |
| color | White-beige |
| BRN | 4778612 |
| Stability: | Hygroscopic |
| InChIKey | FSBUXLDOLNLABB-ISAKITKMSA-N |
| LogP | 0.140 (est) |
Description and Uses
Echinacoside is a phenylethanoid glycoside that has been found in Echinacea and has diverse biological activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals (EC50 = 6.6 μM in a cell-free assay). Echinacoside (10 μg/ml) inhibits hydrogen peroxide-induced production of reactive oxygen species (ROS) and apoptosis in PC12 cells. It reduces increases in plasma alanine aminotransferase (ALT), TNF-α, IL-1β, IL-16, and IL-10 levels and hepatocyte apoptosis induced by LPS/D-galactosamine in a mouse model of acute liver injury when administered at a dose of 60 mg/kg. Echinacoside (20 mg/kg per day for 15 days) prevents loss of dopaminergic neurons in the substantia nigra pars compacta and decreases in striatal dopamine and 3,4-dihydroxyphenylacetic acid (DOPAC) levels in a mouse model of MPTP-induced Parkinson''s disease. It also improves motor performance in the rotarod test in the same model.
Echinacoside Ethanolate is a caffeic acid glycoside, known for its neuroprotective, antiinflammatory and anti-oxidative activities. Also an anti[proliferative towards hypoxia influenced pulmonary artery smooth muscle cells.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| RTECS | LZ5786500 |
| HS Code | 29389090 |
