PRODUCT Properties
| Melting point: | 158-161°C |
| Boiling point: | 368℃ |
| Density | 1.318 |
| refractive index | 1.5168 (estimate) |
| Flash point: | 80 °C |
| storage temp. | Sealed in dry,2-8°C |
| solubility | Acetonitrile (Slightly), Dimethylformamide, DMSO, Ethyl Acetate, Methanol (Slightly) |
| form | Solid |
| pka | 8.71±0.18(Predicted) |
| color | Off-White to Brown |
| λmax | 328nm(MeOH)(lit.) |
| Stability: | Light Sensitive |
| LogP | 1.190 (est) |
| CAS DataBase Reference | 3843-74-1(CAS DataBase Reference) |
Description and Uses
Caffeic acid methyl ester is an ester of a naturally occurring phenolic compound found in P. amplexicaule var. sinense and S. torvum fruits. At 40 mg/kg, it demonstrates antihyperglycemic and antidiabetic activity in diabetic rats, upregulating GLUT4 and regenerating pancreatic β-cells. At 10 mg/kg, it can induce anti-inflammatory and antinociceptive effects in rat models of edema and pain, inhibiting nitric oxide and prostaglandin E2 production, as well as tumor necrosis factor-α release.
Inhibitor of protein tyrosine kinase
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H319-H315 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
| Safety Statements | 24/25 |
| HS Code | 2918.29.7500 |
