Bacitracin zinc salt , fromBacilluslicheniformis,~70,000U/g , 1405-89-6

Synonym(s):
Bacitracin zinc salt;Zinc bacitracin

CAS NO.：1405-89-6

Empirical Formula: C66H101N17O16SZn

Molecular Weight: 1486.07

MDL number: MFCD28168035

EINECS: 215-787-8

PRODUCT Properties

• Melting point: 250 °C (dec.)
• storage temp.: 2-8°C
• solubility: 10 mM HCl: 5 mg/mL, clear, faintly yellow-green
• form: Fine Crystalline Powder
• color: White to light yellow-gray or beige
• PH: Shake 1.0 g with 10 mL of carbon-dioxide-free water R and filter; pH of the filtrate, 6.0-7.5.
• Water Solubility: 5.1 g/L (28 ºC)
• Merck: 13,938
• InChIKey: UCRLQOPRDMGYOA-FWMPYRTHSA-L
• LogP: -1.852 (est)
• EPA Substance Registry System: Zinc bacitracin (1405-89-6)

Description and Uses

Bacitracin zinc is a zinc complex of bacitracin, a polypeptide produced by the growth of an organism of the licheniformis group of Bacillus subtilis. The main components are Bacitracin A, B1 and B2.Bacitracin zinc has antibiotic activity against a variety of Gram-positive bacteria including staphylococci. The zinc complex adds stability to the component, making bacitracin zinc more stable compared to bacitracin.

Bacitracin zinc is a dephosphorylation of the C55-isoprenyl pyrophosphate interference for inhibition of cleavage of Tyr from Met-enkephalin with IC50 of 10 μM.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H319-H412-H317-H335-H315
• Precautionary statements: P264-P280-P302+P352-P321-P332+P313-P362-P273-P501-P264-P280-P305+P351+P338-P337+P313P-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501
• Safety Statements: 22-24/25
• WGK Germany: 3
• F: 3
• HS Code: 29419090