5-Bromo-2-fluoropyridine , 98% , 766-11-0
CAS NO.:766-11-0
Empirical Formula: C5H3BrFN
Molecular Weight: 175.99
MDL number: MFCD01863742
EINECS: 629-380-1
Pack Size | Price | Stock | Quantity |
1G | RMB24.00 | In Stock |
|
5G | RMB36.00 | In Stock |
|
25G | RMB75.20 | In Stock |
|
100G | RMB257.60 | In Stock |
|
others | Enquire |
PRODUCT Properties
Boiling point: | 162-164 °C750 mm Hg(lit.) |
Density | 1.71 g/mL at 25 °C(lit.) |
refractive index | n |
Flash point: | 165 °F |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | DMSO (Slightly), Methanol (Slightly) |
pka | -2.79±0.10(Predicted) |
form | Liquid |
color | Clear colorless yellow |
Specific Gravity | 1.710 |
BRN | 1363171 |
InChIKey | MYUQKYGWKHTRPG-UHFFFAOYSA-N |
Description and Uses
5-Bromo-2-fluoropyridine is a halogenated pyridine that has been used as a molecular scaffold for many Active Pharmaceutical Ingredients (APIs) such as Neuropeptide Y Receptor Y5 Inhibitors, SARS-CoV-2 Major Protease Inhibitors, and Indoleamine-2,3-Dioxygenase-1 Inhibitors in cancer immunotherapy. 5-Bromo-2-fluoropyridine is also an ideal building block for semiconductors, due to its aromaticity and electron deficiency. A host material of 5-(5-(2,4,6-triiso-propylphenyl)pyridin-2-yl)-5H-benzo[d]benzo-[4,5]imidazo[1,2-a]imidazole is synthesized from 5-bromo-2-fluoropyridine for OLED applications.
5-Bromo-2-fluoropyridine is used in the synthesis of heteroaromatic and aniline derivatives of piperidines as potent ligands used for vesicular acetylcholine transport. Also used in the synthesis of benzofurano[3,2-d]pyrimidin-2-one derived inhbitors.
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H315-H319-H335 |
Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
Hazard Codes | Xi,Xn |
Risk Statements | 36/37/38-22 |
Safety Statements | 26-36/37-37/39 |
RIDADR | UN2810 |
WGK Germany | 3 |
Hazard Note | Irritant |
HazardClass | 6.1 |
PackingGroup | III |
HS Code | 29339900 |