Home Categories Pharmaceutical intermediates 5-Bromo-2-fluoropyridine
A1264112

5-Bromo-2-fluoropyridine , 98% , 766-11-0

CAS NO.:766-11-0

Empirical Formula: C5H3BrFN

Molecular Weight: 175.99

MDL number: MFCD01863742

EINECS: 629-380-1

Pack Size Price Stock Quantity
1G RMB24.00 In Stock
5G RMB36.00 In Stock
25G RMB75.20 In Stock
100G RMB257.60 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Boiling point: 162-164 °C750 mm Hg(lit.)
Density  1.71 g/mL at 25 °C(lit.)
refractive index  n20/D 1.5325(lit.)
Flash point: 165 °F
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
solubility  DMSO (Slightly), Methanol (Slightly)
pka -2.79±0.10(Predicted)
form  Liquid
color  Clear colorless yellow
Specific Gravity 1.710
BRN  1363171
InChIKey MYUQKYGWKHTRPG-UHFFFAOYSA-N

Description and Uses

5-Bromo-2-fluoropyridine is a halogenated pyridine that has been used as a molecular scaffold for many Active Pharmaceutical Ingredients (APIs) such as Neuropeptide Y Receptor Y5 Inhibitors, SARS-CoV-2 Major Protease Inhibitors, and Indoleamine-2,3-Dioxygenase-1 Inhibitors in cancer immunotherapy. 5-Bromo-2-fluoropyridine is also an ideal building block for semiconductors, due to its aromaticity and electron deficiency. A host material of 5-(5-(2,4,6-triiso-propylphenyl)pyridin-2-yl)-5H-benzo[d]benzo-[4,5]imidazo[1,2-a]imidazole is synthesized from 5-bromo-2-fluoropyridine for OLED applications.

5-Bromo-2-fluoropyridine is used in the synthesis of heteroaromatic and aniline derivatives of piperidines as potent ligands used for vesicular acetylcholine transport. Also used in the synthesis of benzofurano[3,2-d]pyrimidin-2-one derived inhbitors.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-22
Safety Statements  26-36/37-37/39
RIDADR  UN2810
WGK Germany  3
Hazard Note  Irritant
HazardClass  6.1
PackingGroup  III
HS Code  29339900

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