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A1233112

BOP Reagent , 98% , 56602-33-6

Synonym(s):
Benzotriazole-1-yl-oxy-tris-(dimethylamino)-phosphoniumhexafluorophosphate, Castro′s Reagent;BOP;BOP Reagent;Castros reagent

CAS NO.:56602-33-6

Empirical Formula: C12H22F6N6OP2

Molecular Weight: 442.29

MDL number: MFCD00011948

EINECS: 260-279-1

Pack Size Price Stock Quantity
5G RMB32.80 In Stock
25G RMB63.20 In Stock
100G RMB194.40 In Stock
500G RMB888.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: >130 °C (dec.)(lit.)
Flash point: 138°C
storage temp.  2-8°C
solubility  methanol: 25 mg/mL, clear
form  Powder
color  White to off-white
Water Solubility  Soluble in methanol, acetone and dichloromethane. Insoluble in water.
Decomposition  138 ºC
Sensitive  Moisture & Light Sensitive
BRN  4287025

Description and Uses

1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium hexafluorophosphate is used as a reagent for peptide coupling, lactonization, selective esterification, amidation of alfa amino acids without racemization and synthesis of magnolamide for antioxidative activity and catalyst for 9-acridinecaroboxamide derivative. It is also used as a precursor for the synthesis of phenyl esters of amino acids. It acts as a substitute for (Benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) reagent.

Safety

Symbol(GHS) 
GHS02,GHS07
Signal word  Danger
Hazard statements  H228-H315-H335
Precautionary statements  P210-P240-P241-P261-P264-P302+P352
Hazard Codes  Xi,E,F
Risk Statements  37/38-44-36/37/38-11-2
Safety Statements  24/25-37/39-36-26-35-36/37/39
RIDADR  UN 1325 4.1/PG 2
WGK Germany  3
8-10-21
Hazard Note  Irritant
HazardClass  4.1
PackingGroup 
HS Code  29339980

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