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A1075350

Prednisolone(Predonine) , ≥98% , 50-24-8

Synonym(s):
1,4-Pregnadiene-11β,17α,21-triol-3,20-dione;11β,17α,21-Trihydroxy-1,4-pregnadiene-3,20-dione;1-Dehydrocortisol;1-Dehydrohydrocortisone;Prednisolone

CAS NO.:50-24-8

Empirical Formula: C21H28O5

Molecular Weight: 360.45

MDL number: MFCD00003649

EINECS: 200-021-7

Pack Size Price Stock Quantity
1g RMB79.20 In Stock
5g RMB199.20 In Stock
25g RMB639.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 240 °C (dec.) (lit.)
alpha  D25 +102° (dioxane)
Boiling point: 412.46°C (rough estimate)
Density  1.0963 (rough estimate)
refractive index  100 ° (C=1, Dioxane)
Flash point: 2℃
storage temp.  2-8°C
solubility  Very slightly soluble in water, soluble in ethanol (96 per cent) and in methanol, sparingly soluble in acetone, slightly soluble in methylene chloride. It shows polymorphism (5.9).
pka 12.46±0.70(Predicted)
form  powder
color  White to Off-White
Water Solubility  2.225g/L(25 ºC)
Merck  14,7721
BRN  1354103
BCS Class 1
InChIKey OIGNJSKKLXVSLS-VWUMJDOOSA-N
CAS DataBase Reference 50-24-8(CAS DataBase Reference)
EPA Substance Registry System Prednisolone (50-24-8)

Description and Uses

Prednisolone is the active metabolite of the synthetic corticosteroid prednisone , which is used in the suppression of inflammation and autoimmunity, as well as in other conditions. It alters gene expression through both the glucocorticoid and mineralocorticoid receptors.

Prednisolone is used for the same indications as all corticosteroids: rheumatism, polyarthritis, bronchial asthma, neurodermatitis, and eczema.

Safety

Symbol(GHS) 
GHS08
Signal word  Danger
Hazard statements  H360FD
Precautionary statements  P201-P202-P280-P308+P313-P405-P501
Hazard Codes 
Hazardous Substances Data 50-24-8(Hazardous Substances Data)
Toxicity LD50 oral in mouse: 1680mg/kg

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