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A0966212

Arjunolic acid , 95% , 465-00-9

Synonym(s):
2,3,23-Trihydroxyolean-12-en-28-oic acid

CAS NO.:465-00-9

Empirical Formula: C30H48O5

Molecular Weight: 488.7

MDL number: MFCD11113458

Pack Size Price Stock Quantity
1MG RMB1591.20 In Stock
5mg RMB4799.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 332-334 °C
Boiling point: 606.0±55.0 °C(Predicted)
Density  1.19±0.1 g/cm3(Predicted)
storage temp.  -20°C
solubility  Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form  Powder
pka 4.62±0.70(Predicted)
color  White to off-white

Description and Uses

Arjunolic acid is a triterpene that has been found in T. arjuna and has diverse biological activities, including antioxidant, anticancer, and anti-inflammatory properties. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals in a cell-free assay when used at a concentration of 0.8 mM. Arjunolic acid (20 mg/kg for four days) prevents arsenic-induced decreases in the activity of superoxide dismutase (SOD1), catalase, GST, and glutathione reductase in mouse brain. It reduces tumor growth in an Ehrlich murine spontaneous adenocarcinoma model when administered at doses of 100 and 250 mg/kg for 20 days. Arjunolic acid reduces renal fibrosis and increases in kidney TNF-α and IL-1β levels induced by cisplatin in mice when administered at doses of 100 and 250 mg/kg per day for 10 days.

Arjunolic Acid is a naturally occurring terpenoid which displays anti-inflammatory activity as well as protective effects during chemical induced organ pathophysiology.

Safety

WGK Germany  3

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