A0773912
AZD8055 , ≥99% , 1009298-09-2
CAS NO.:1009298-09-2
Empirical Formula: C25H31N5O4
Molecular Weight: 465.54
MDL number: MFCD16660191
Pack Size | Price | Stock | Quantity |
10MG | RMB239.20 | In Stock |
|
50MG | RMB798.40 | In Stock |
|
200MG | RMB1791.20 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 204 - 207°C |
Boiling point: | 694.3±65.0 °C(Predicted) |
Density | 1.248 |
storage temp. | -20°C |
solubility | Soluble in DMSO (up to 30 mg/ml) |
form | Yellow powder. |
pka | 14.20±0.10(Predicted) |
color | Yellow |
Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months. |
Description and Uses
AZD8055 (1009298-09-2) is a potent and highly selective inhibitor of mammalian target of rapamycin kinase (mTOR) kinase (IC50 = 0.8 nM).1,2 ?mTOR acts as a nutrient/energy/redox sensor and a controller of protein synthesis – as such it is a very important target for cancer research.? It has been investigated as a potential chemotherapeutic for various cancers.3-7
A novel ATP-competitive inhibitor of mTOR with an IC50 of 0.8 nM.
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H335-H319-H315 |
Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
Safety Statements | 24/25 |
HS Code | 29335990 |