Home Categories Pharmaceutical intermediates 3-Acetyl-2,5-dichlorothiophene
A0759512

3-Acetyl-2,5-dichlorothiophene , 98% , 36157-40-1

Synonym(s):
2,5-Dichloro-3-thienyl methyl ketone

CAS NO.:36157-40-1

Empirical Formula: C6H4Cl2OS

Molecular Weight: 195.07

MDL number: MFCD00014522

EINECS: 252-893-3

Pack Size Price Stock Quantity
5G RMB35.20 In Stock
25G RMB116.80 In Stock
100G RMB368.00 In Stock
500G RMB1286.40 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 37-40 °C (lit.)
Boiling point: 120-122°C 4mm
Density  1.4514 (estimate)
Flash point: >230 °F
storage temp.  Keep in dark place,Inert atmosphere,2-8°C
form  solid
color  White to Yellow to Orange
BRN  121288
CAS DataBase Reference 36157-40-1(CAS DataBase Reference)
NIST Chemistry Reference 2,5-Dichloro-3-thienyl methyl ketone(36157-40-1)

Description and Uses

3-Acetyl-2,5-dichlorothiophene may be used in the following syntheses:

  • substituted chalcones
  • AL-4623A and AL-4862 (brinzolamide), inhibitors of topical carbonic anhydrase
  • 2,5-dichlorothiophene-3-carboxylic acid, which is the starting reagent required for the synthesis of 2,5-dichloro-N-(substituted amino-carbonothioyl)thiophene-3-carboxamides and 2-(substituted amino)-4H-thieno[3,2-e]-1,3-thiazin-4-ones

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338
Hazard Codes  Xn,Xi
Risk Statements  20/21/22-36/37/38
Safety Statements  26-36-36/37/39-22-36/37
WGK Germany  3
Hazard Note  Irritant
HS Code  29349990

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