Agmatine Sulfate , 98% , 2482-00-0

Synonym(s):
N-(4-Aminobutyl)guanidine sulfate salt;1-Amino-4-guanidinobutane sulfate salt;4-Guanidinobutylamine sulfate salt

CAS NO.：2482-00-0

Empirical Formula: C5H16N4O4S

Molecular Weight: 228.27

MDL number: MFCD00013109

EINECS: 219-617-3

PRODUCT Properties

• Melting point: 234-238 °C(lit.)
• RTECS: ME8413000
• storage temp.: Keep in dark place,Inert atmosphere,Room temperature
• solubility: H₂O: 50 mg/mL
• form: powder
• color: white to off-white
• Water Solubility: Soluble in water, nearly insoluble in alcohol
• Merck: 14,188
• BRN: 3918807
• InChI: InChI=1S/C5H14N4.H2O4S/c6-3-1-2-4-9-5(7)8;1-5(2,3)4/h1-4,6H2,(H4,7,8,9);(H2,1,2,3,4)
• InChIKey: PTAYFGHRDOMJGC-UHFFFAOYSA-N
• SMILES: C(CCCN)NC(N)=N.S(O)(O)(=O)=O
• CAS DataBase Reference: 2482-00-0(CAS DataBase Reference)

Description and Uses

Agmatine sulfate is the sulfate of the Agmatine. Agmatine is an aninoguanidine that is naturally derived from the arginine. It can exert modulatory effect on many molecular targets such as neurotransmitter systems, opioid analgesia, ion channels, and nitric oxide (NO) synthesis and polyamine metabolism. It has been also found that it can reverse the pain induced from inflammation, neuropathy, and spinal cord injury. Those effects make it a potential candidate for multiple pharmacological applications in the future.

Agmatine is an intermediate in the biosynthesis of the polyamines putrescine and spermine. Agmatine binds with high affinity to α2-adrenergic receptors and imidazoline binding sites and produces blockade of the NMDA-receptor associated cation channels. Agmatine is a competitive inhibitor of nitric oxide synthase activity owing to mimicry of the natural NOS substrate arginine.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P305+P351+P338
• Safety Statements: 22-24/25
• WGK Germany: 3
• F: 10
• HS Code: 29252900