3-[2-(2-Aminoethoxy)ethoxy]-propanoic acid , 98% , 791028-27-8
Pack Size | Price | Stock | Quantity |
100mg | RMB207.20 | In Stock |
|
250mg | RMB604.80 | In Stock |
|
1G | RMB799.20 | In Stock |
|
5g | RMB2399.20 | In Stock |
|
others | Enquire |
PRODUCT Properties
Boiling point: | 331.5±27.0 °C(Predicted) |
Density | 1.142±0.06 g/cm3(Predicted) |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
pka | 4.27±0.10(Predicted) |
form | Solid |
color | White to off-white |
Description and Uses
Amino-PEG2-acid is a PEG reagent containing an amino group with a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Amino-PEG2-C2-acid is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-PEG2-C2-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Safety
Symbol(GHS) | ![]() GHS07 |
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P280-P305+P351+P338 |
HS Code | 2918999090 |