4-Aminophenylboronic acid pinacol ester , 98% , 214360-73-3

Synonym(s):
2-(4-Aminophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)aniline;4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzeneamine;4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenylamine;4-Aminophenylboronic acid, pinacol cyclic ester

CAS NO.：214360-73-3

Empirical Formula: C12H18BNO2

Molecular Weight: 219.09

MDL number: MFCD02258965

EINECS: 629-061-7

PRODUCT Properties

• Melting point: 165-169 °C (lit.)
• Boiling point: 340.0±25.0 °C(Predicted)
• Density: 1.05±0.1 g/cm3(Predicted)
• storage temp.: Keep in dark place,Sealed in dry,Room Temperature
• solubility: Chloroform
• form: Crystalline Powder
• pka: 4.24±0.10(Predicted)
• color: Almost white to light beige
• Water Solubility: Insoluble
• InChI: InChI=1S/C12H18BNO2/c1-11(2)12(3,4)16-13(15-11)9-5-7-10(14)8-6-9/h5-8H,14H2,1-4H3
• InChIKey: ZANPJXNYBVVNSD-UHFFFAOYSA-N
• SMILES: C1(N)=CC=C(B2OC(C)(C)C(C)(C)O2)C=C1
• CAS DataBase Reference: 214360-73-3(CAS DataBase Reference)

Description and Uses

4-Aminophenylboronic acid pinacol ester can be used as a reagent for:

• The preparation of substituted 3-phenyl-4H-1-benzopyran-4-ones by reacting with iodochromones via Pd catalyzed Suzuki-Miyaura cross-coupling reaction.
• Mercury(II) detection by fluorometry with new fluorogenic indicators based on through-bond energy transfer from pentaquinone to rhodamine.
• Rhodium-catalyzed amination reactions.
• Palladium-catalyzed Suzuki cross-coupling to synthesize potential antitubercular and antimicrobial compounds.

It can also be used to prepare:

• Hexaphenylbenzene derivatives as a potential bioprobe and multichannel keypad system.
• Pyromellitic diimide-based polymer as matrix for solution-processable n-channel field-effect transistors.
• Alternating copolymers of oligoarylenes and naphthalene bisimides as low band-gap semiconductors with electrochemical and spectroelectrochemical behavior.
• γ-secretase modulators in the treatment of amyloid β formation.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-36-37/39
• WGK Germany: 3
• TSCA: No
• HazardClass: IRRITANT
• HS Code: 29319090