Amyloid β Protein Fragment 1-42 , ≥95%(HPLC) , 107761-42-2

Synonym(s):
β-Amyloid Peptide (1-42), Rat;DAEFGHDSGFEVRHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

CAS NO.：107761-42-2

Empirical Formula: C203H311N55O60S1

Molecular Weight: 4514.04

MDL number: MFCD00163049

PRODUCT Properties

• storage temp.: -20°C
• solubility: Soluble in ammonium hydroxide, pH >9. Also soluble in DMSO.
• form: Lyophilized
• color: Lyophilized White
• Sequence: H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH
• InChIKey: XPESWQNHKICWDY-QYFPAAMGSA-N
• CAS DataBase Reference: 107761-42-2(CAS DataBase Reference)

Description and Uses

Amyloid β-Peptide (1-42) (human)[107761-42-2], a major component of amyloid plaques, accumulates in neurons of Alzheimer's disease brains. Aβ(s) peptides, their peptide fragments and mutated fragments are used to study a wide range of metabolic and regulatory functions including activation of kinases, regulation of cholesterol transport, function as a transcription factor, and regulators of inflammation. Aβ(s) peptides and their peptide fragments are also used to study oxidative stress, metal binding and mechanisms of protein cross-linking in the context of diseases such as Alzheimer's disease and neurodegeneration.

Safety

• Safety Statements: 24/25
• WGK Germany: 3
• HS Code: 29332900