Acibenzolar-S-methyl , Analysis standard , 135158-54-2

Synonym(s):
S-Methyl-1,2,3-benzothiadiazole-7-carbothioate

CAS NO.：135158-54-2

Empirical Formula: C8H6N2OS2

Molecular Weight: 210.28

MDL number: MFCD03427349

EINECS: 420-050-0

PRODUCT Properties

• Melting point: 134-135℃
• Boiling point: 267°C (rough estimate)
• Density: 1.450
• vapor pressure: 4.4 x 10^-4 Pa (25 °C)
• refractive index: 1.5690 (estimate)
• storage temp.: 0-6°C
• solubility: Chloroform (Slightly), Methanol (Very Slightly)
• Water Solubility: 7.7 mg l^-1 (25 °C)
• pka: -3.90±0.50(Predicted)
• color: Off-White to Light Beige
• LogP: 3.100
• EPA Substance Registry System: Acibenzolar-S-methyl (135158-54-2)

Description and Uses

Acibenzolar-S-methyl (Novartis) has attracted special attention because it acts against a very wide range of plant diseases but does not directly affect the growth or metabolism of the causal organisms. It is known to act by stimulating systemic activated resistance (SAR) in the treated plant. The well-established compound probenazole, which for some years has been the leading treatment for rice blast in Japan, is thought to act in a similar way. Pathogen resistance to probenazole has not developed, and such stability of performance may well be a general feature of SAR-inducing compounds.

CGA245704 is used to control a range of diseases in wheat and it is being developed for use on rice, bananas, vegetables and tobacco.

Safety

• Symbol(GHS): GHS07,GHS09
• Signal word: Warning
• Hazard statements: H315-H317-H319-H335-H410
• Precautionary statements: P273-P280-P302+P352-P305+P351+P338
• Hazard Codes: Xi,N
• Risk Statements: 36/37/38-43-50/53
• Safety Statements: 24/25-37-46-59-60-61
• RIDADR: UN 3077 9 / PGIII
• WGK Germany: 3
• Hazardous Substances Data: 135158-54-2(Hazardous Substances Data)
• Toxicity: LD50 in rats (mg/kg): >2000 orally; >2000 dermally (Ruess)