Home Categories Biochemical Engineering 2-Amino-6-chloropurine
A0706712

2-Amino-6-chloropurine , 98% , 10310-21-1

Synonym(s):
2-Amino-6-chloropurine;6-Chloro-2-purinamine;6-Chloroguanine

CAS NO.:10310-21-1

Empirical Formula: C5H4ClN5

Molecular Weight: 169.57

MDL number: MFCD00075252

EINECS: 233-686-7

Pack Size Price Stock Quantity
1G RMB23.20 In Stock
5G RMB39.20 In Stock
25G RMB59.20 In Stock
100G RMB197.60 In Stock
250G RMB439.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: >300 °C (lit.)
Boiling point: 279.76°C (rough estimate)
Density  1.4937 (rough estimate)
refractive index  1.6110 (estimate)
storage temp.  2-8°C
solubility  Solubility in 1mol/L NaOH
pka 6.65±0.20(Predicted)
form  Powder
color  White to yellow
Water Solubility  1.7 g/L (20 ºC)
BRN  9626
InChI InChI=1S/C5H4ClN5/c6-3-2-4(9-1-8-2)11-5(7)10-3/h1H,(H3,7,8,9,10,11)
InChIKey RYYIULNRIVUMTQ-UHFFFAOYSA-N
SMILES N1C2C(=NC(N)=NC=2Cl)NC=1
CAS DataBase Reference 10310-21-1(CAS DataBase Reference)
EPA Substance Registry System 6-Chloro-2-aminopurine (10310-21-1)

Description and Uses

2-Amino-6-chloropurine is a precursor in the synthesis of nucleoside analogs with antiviral activity against Epstein-Barr virus (EBV) and human herpes virus 6 (HHV-6).

2-Amino-6-chloropurine may be used:

  • in the enzymatic synthesis of 2′-deoxyguanosine
  • in the synthesis of 9-alkyl purines
  • in the synthesis of (R)- and (S)-N-(2-phosphonomethoxypropyl) derivatives of purine and pyrimidine bases

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P201-P202-P261-P264b-P271-P280i-P302+P352-P304+P340-P305+P351+P338-P308+P313-P332+P313-P362+P364-P403+P233-P501c
Hazard Codes  Xi,Xn
Risk Statements  20/21/22-36/37/38
Safety Statements  22-24/25-36-26
WGK Germany  3
RTECS  UO7502000
10
Hazard Note  Irritant/Keep Cold
HazardClass  IRRITANT, KEEP COLD
HS Code  29339900

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